Baccharis megapotomica

Trichothecenes are a series of sesquiterpene compounds that have been isolated either as fungal metabolites or from the Brazilian shrubs Baccharis megapotomica and Baccharis coridifolia. The first... 

Jarvis, B.B., Midiwo, J.O., Tuthill, D., and Bean, G.A. (1981). Interaction between the antibiotic trichothecenes and the higher plant Baccharis megapotomica. Science 214, 460-462. 

The detection of the macrocyclic baccharanoid trichothecenes in Baccharis megapotomica (Kupchan et al., 1977) and B. cordifolia... 

Busam and Habermahl, 1982) in relatively high concentrations suggests that some plant species may be naturally resistant to the effects of macrocyclic trichothecenes. Mechanisms for such resistance have been speculated to be a rapid detoxification process within the plant cells (Jarvis et al., 1981). However baccharinoid, the macrocyclic trichothecene from Baccharis species, exhibits essentially the same degree of phytotoxicity as roridin A and E when applied to tissues of other plant species. Therefore, the vivo conversion of roridins to the baccharanoids by B, megapotomica should not be interpreted as a detoxification process (Cutler and Jarvis, 1985). 

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