Azorellane diterpenes

Figure 2 Selected mulinane and azorellane diterpenes isolated from Azorella ssp, cushion plants of the high southern Andes. References in text.

These plants produce an array of diterpenes of unusual carbon skeletons of the mulinane and azorellane type 1-5 (fig. 2) and have been used in folk medicine to treat a variety of lung conditions and as pain relievers. Some of the isolated compounds proved to be analgesic, anti-inflammatory and also moderately effective against malaria-causing protozoa (Delporte... 

Figure 20. Possible biosynthetic route to mulinane, azorellane, yaretane, and madreporane carbon skeletons of diterpenes isolated from high elevation Azorella cushion plants, according to Loyola et ah, 2002. Note the unusual demethylation step in the azorellane - yaretane conversion.

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See also in sourсe #XX -- [ ]

See also in sourсe #XX -- [ ]

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