Enalapril Azathioprine

ACE INHIBITORS AZATHIOPRINE Risk of anaemia with captopril and enalapril and leukopenia with captopril The exact mechanism is uncertain. Azathioprine-induced impairment of haematopoiesis and ACE inhibitor-induced l in erythropoietin may cause additive effects. Enalapril has been used to treat post-renal transplant erythrocytosis Monitor blood counts regularly... 

Antiviral agents acyclovir, amantadine, azidofhymidine Diuretics furosemide, hydrochlorothiazide, efhacrynic acid ACE inhibitors captopril, enalapril, ramipril, delapril, quinapril Antineoplastics methotrexate, azathioprine, doxorubicin, 5-fluouracil Antiepileptics valproic acid (from Ref. [95])... 

Anaemia caused by captopril and enalapril has been seen in kidney transplant patients and in dialysis patients (see ACE inhibitors and Angiotensin II receptor antagonists + Epoetin , p.25). The evidence that this effect can be potentiated by azathioprine is limited, but it would be prudent to monitor well if these drugs are used together. 

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