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Autonomous parvovirus

Fisher RE, Mayor HD. The evolution of defective and autonomous parvoviruses. J TheorBiol 1991 149 429-39. [Pg.79]

Other vectors including polio (32), retrovirus (33), bacteria (34), and autonomous parvovirus (35) are all potential oncolytic vectors under development. Autonomous parvovirus is a nonenveloped, single- stranded DNA virus that replicates in cells in the cytoplasm of dividing and nondividing tumor cells. Its envelope can be modified, similar to retroviruses, to contain ligand moieties to target cell surfece receptors. It has been used in vaccine production where it showed low toxicity in human applications (11). Currently, the H-1 strain is being evaluated in the clinic (4). [Pg.148]

Palmer GA, Tattersall P. Autonomous parvoviruses as gene transfer vehicles. Contrib Microbiol 2000 4 178-202. [Pg.162]

See other pages where Autonomous parvovirus is mentioned: [Pg.169]    [Pg.240]    [Pg.445]    [Pg.69]    [Pg.52]    [Pg.146]    [Pg.169]    [Pg.240]    [Pg.445]    [Pg.69]    [Pg.52]    [Pg.146]    [Pg.441]    [Pg.54]   
See also in sourсe #XX -- [ Pg.148 ]



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