Aurines

VII,10. AMMONIUM SALT OF AURIN TRICARBOXYLIC ACID ( ALUMINON )... 

Formaldehyde condenses with sahcyhc acid in the presence of nitrite-containing sulphuric acid to give aurin tiicarboxyhc acid this is converted by ammonia solution into the ammonium salt, which is employed as a reagent for aluminium ( aluminon ) ... 

Alnminon (qualitative test for aluminum). The reagent consists of 0.1% solution of the ammonium salt of aurin tricarboxylic acid. A bright red precipitate, persisting in alkaline solution, indicates aluminum. 

Indicator solutions a number of indicator solutions are listed in this section under the names of the indicators e.g., alizarin, aurin, azolitmin, et al., which follow alphabetically. See also various index entries. 

Rosolic acid, aurin, corallin, corallinphthalein, 4,4 -dihydroxy-fuchsone, 4,4 -dihydroxy-3-methyl-fuchsone (indicator) dissolve 0.5 g in 50 mL alcohol and dilute with water to 100 mL. Salicyl yellow (indicator) see alizarin yellow GG. 

Aurin tricarboxylic acid [4431-00-9] M 422.4, m 300". The acid is dissolved in aqueous NaOH, NaHS03 solution is added until the colour is discharged and then the tricarboxylic acid is ppted with HCI [Org Synth Coll Vol I 54 1947]. Do not extract the acid with hot water because it softens forming a viscous mass. Make a solution by dissolving in aqueous NH3. See Aluminon for the ammonium salt. 

The kidney function confers high impact on diug kinetics when a high fraction (fren) of the diug dose (D) is eliminated in urine (Aurine). The renal fraction (fren) can be underestimated when bioavailability (F) is neglected. The renal clearance, however, can be derived from the amount eliminated by the renal route (Aurine) independent from bioavailability (F). 

To examine the cavitational effect of ultrasound on bright-red complex of aluminon adsorbed on Al(OH)3, in our experiments, 25 ml of 0.005 M aluminium sulphate was treated with 5 ml of 1% aluminon (triammonium aurine-tricarboxylate). This adsorption complex was sonicated for 10, 20 and 30 min, while the control sample was agitated for the same duration with a magnetic stirrer. The turbidity in sonicated sample increased, as time of sonication increased compared to the unsonicated condition (Table 9.18 and Fig. 9.4). In sonicated sample, the colour of the adsorption complex was dark compared to the control sample and the settlement of the adsorption complex was also slower due to the smaller size particle of the complex. 

Aurin tricarboxylate (also known as aluminon) forms fairly stable complexes with beryllium Log Kx values of 5.38 (160) and 4.54 (161) have been reported. In the 1950s this ligand was examined as a possible antidote to beryllium poisoning in rats, but although it reduced the toxicity, serious side effects were noted for further details see the review by Wong and Woollins (20). 

US Military Specification requirements and tests are discussed in Specification MIL-P-20466. Calorimetric method for determination of Aurine is given in MIL-STD-286A (I960)... 

The kinetic spectra of Aurine, Indanthrene Yellow, and Golden-Orange are similar to those of Chlorophyll. 

Aurine Coraiiin or 4,4 -Dihydroxyruch one, called in CA 4-[Bis(p-Hydroxyphenyl) methylene1-2.5-eyclohexadien l-an< and in ... 

A urine is used in small amt (ca 0.23%) as a component of EC Propellant for Blank Cartridges and Fragmentation Hand Grenades. A gravimetric method of aurine detn in EC propellant is described in US Army specification No 50-13-8B, while a colorimetric method is given in US Military Standard MIL-STD-286A(1 >60)... 

A historical discussion on the nomenclature of aurine is given in Beil 8, 361... 

Aurine Perchlorate, C H140j + HC104 + Ha0 red crysts, forming on prolonged heating an anhydrous salt. Was first prepd by Hofmann (Ref 2) by treating aurin in AcOH with coned HC104. It was also obtained by Pfeiffer (Ref 3)... 

Aurine, Azido C HuN301 and Diazido-ClsH N0O3 Derivatives were not found in Beil or CA through 1956... 

N 11.91% brownish microscopic needles mp ca 140° when carefully heated. It is a mild explosive, sol in ale, nearly insol in w, eth, chlf or benz. Was prepd by treating 1 part of powdered aurin with 4 ps nitric acid (d 1.51) in the cold. The positions of the nitro groups are not given... 

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