Aurin tricarboxylate, complex with beryllium

Aurin tricarboxylate (also known as aluminon) forms fairly stable complexes with beryllium Log Kx values of 5.38 (160) and 4.54 (161) have been reported. In the 1950s this ligand was examined as a possible antidote to beryllium poisoning in rats, but although it reduced the toxicity, serious side effects were noted for further details see the review by Wong and Woollins (20). 

Beryllium poisoning is treated with large doses of sodium salicylate, or smaller doses of aurine tricarboxylic acid. The latter, which has three salicylate moieties linked to a central carbon atom, does not assist the excretion of this metal, as salicylate does, but keeps it, in the tissues, as a very insoluble complex. 

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See also in sourсe #XX -- [ ]

See also in sourсe #XX -- [ ]

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