Asymmetric polymerase chain reaction

Electrophysiological studies often demonstrate multiple, asymmetric mononeuropathies, usually axonal in type, that cannot be localized to typical sites of entrapment (Keswani et al. 2002). CSF analysis reveals nonspecific abnormalities, such as elevated protein and mild mononuclear pleocytosis. Polymerase chain reaction (PCR) for CMV DNA and nerve or muscle biopsy may provide more specific diagnostic data (Roullet et al. 1994). 

Shyamala V, Ames GF (1989) AmpUfication of bacterial genomic DNA by the polymerase chain reaction and direct sequencing after asymmetric amplification application to the study of petiplasmic permeases. J Bacteriol 171(3) 1602-1608... 

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