Asthma drugs inhibitory effects

Alpha-adrenergic antagonists are used primarily as antihypertensive drugs because of their ability to block vascular alpha-1 receptors. Beta-adrenergic antagonists (beta blockers) are administered primarily for their inhibitory effects on myocardial function and are used in the prevention and treatment of hypertension, angina pectoris, arrhythmias, and myocardial reinfarction. Many of the drugs introduced in this chapter are discussed further in chapters that deal with the specific clinical conditions (e.g., hypertension, asthma, and other disorders). 

As a further example of the promising properties of / terphenyl metabolites, we wish to mention here the benzofuranoid compounds isolated from the fruiting bodies of Poliporus leucomelas, and in particular Bl-III (69), displaying an inhibitory effect on 5-lipoxygenase comparable to that of a therapeutic drug for asthma. 

VI. Predicting the Clinical Efficacy of Asthma Drugs from Their Inhibitory Effect on Allergen Bronchoprovocation... 

B. Correlations Between Inhibitory Effects of Asthma Drugs on Allergen Challenge and Their Clinical Efficacy... 

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