Aspirin Free Pain Relief

Caplets, extended release 500 and 650 mg (ofc) Aspirin Free Pain Relief Hudson), Genapap Extra Strength, Genebs Extra Strength (Goldline), Tapanol Extra Strength (Republic), Tylenol Extended Relief (McNeil-CPC)... 

OTC Acephen,Apacet, Arthritis Pain Formula, Aspirin-Free Pain Relief, Feverall, Genapap, Liquiprin, Neopap, Panadol, Tapanol, Tempra, Tylenol... 

The well-known drug Aspirin can demonstrate the various stages in the life of a drug substance. It was known since ancient times that the bark and leaves of the willow tree can provide relief from pain and fever. In 1832, the German chemist Piria isolated salicylic acid as the active substance in the plant material. Salicylic acid became the lead substance for further development. Soon a synthetic route was developed that replaced the tedious extraction process. Salicylic acid was used as a pain remedy, but because of its high acidity it had severe side effects when applied orally. In 1887, Felix Hoffmann, a chemist at Bayer AG, realized that the ester form of salicylic acid, acetylsalicylic acid, had fewer side effects and was even more efficacious than the free acid. The Bayer Company marketed the ester under the trade name Aspirin, which soon became the number one selling drug worldwide and is still a synonym for pain relief today. 

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