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Ascorbate Changes during Aging

Old reports describing decreases in ascorbate with aging in many mammals exist (Kirk, 1962). A clear decrease in serum levels of ascorbic acid (measured by colorimetry) was found in male Wistar rats between 3 and 12 months of age but no changes were observed between 12- and 24-month-old rats (De and Darad, 1991). In the same study no changes in liver ascorbate levels were found among the three [Pg.170]

Various mammals Various tissues Decrease Colorimetry Kirk, 1962 [Pg.172]

Wistar rat (male) 3 to 12 months Serum Decrease (No change 12-24) Colorimetry De and Darad, 1991 [Pg.172]

Wistar rat (female) 3 to 30 months Liver microsomes Increase — Devasagayam, 1986 [Pg.172]

Von Zglinicki, T., Wiswedel, I., Trumper, L., and Agustin, W., 1991, Morphological changes of isolated rat liver mitochondria during Fe /ascorbate-induced peroxidation and the effect of thioctic acid, Mech. Aging Dev. 57 233-246. [Pg.187]

See other pages where Ascorbate Changes during Aging is mentioned: [Pg.170]    [Pg.172]    [Pg.449]    [Pg.170]    [Pg.172]    [Pg.449]    [Pg.57]    [Pg.170]    [Pg.184]    [Pg.208]    [Pg.492]    [Pg.171]    [Pg.173]    [Pg.160]    [Pg.1087]    [Pg.378]    [Pg.176]    [Pg.238]    [Pg.52]    [Pg.87]    [Pg.43]   


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Changes during

During aging, changes

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