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Aryl groups, coupling

If the NH2 is substituted by an alkyl or aryl group coupling takes place, e.g.,... [Pg.282]

As indicated in the introduction, the photolysis of halothiophenes and halofurans in the presence of arenes to yield arylheterocycles has been reviewed. In this reaction the aryl group couples at the position on the heterocycle formerly occupied by the halogen. The reaction is particularly efficient if a ketone or... [Pg.243]

HIC media are composed of resins that contain alkyl or aryl groups coupled to an inert, porous matrix made of spherical particles with a high internal surface area. Agarose is the main matrix suitable for preparing... [Pg.160]

Tandem cyclization/3-substitution can be achieved starting with o-(trifluoro-acetamido)phenylacetylenes. Cyclization and coupling with cycloalkenyl trif-lates can be done with Pd(PPh3)4 as the catalyst[9]. The Pd presumably cycles between the (0) and (II) oxidation levels by oxidative addition with the triflate and the reductive elimination which completes the 3-alkenylation. The N-protecting group is removed by solvolysis under the reaction conditions, 3-Aryl groups can also be introduced using aryl iodides[9]. [Pg.23]

A reaction of aryl diazonium salts that does not involve loss of nitrogen takes place when they react with phenols and arylamines Aryl diazonium ions are relatively weak elec trophiles but have sufficient reactivity to attack strongly activated aromatic rings The reaction is known as azo coupling two aryl groups are joined together by an azo (—N=N—) function... [Pg.950]

Sulfonic acids are prone to reduction with iodine [7553-56-2] in the presence of triphenylphosphine [603-35-0] to produce the corresponding iodides. This type of reduction is also facile with alkyl sulfonates (16). Aromatic sulfonic acids may also be reduced electrochemicaHy to give the parent arene. However, sulfonic acids, when reduced with iodine and phosphoms [7723-14-0] produce thiols (qv). Amination of sulfonates has also been reported, in which the carbon—sulfur bond is cleaved (17). Ortho-Hthiation of sulfonic acid lithium salts has proven to be a useful technique for organic syntheses, but has Httie commercial importance. Optically active sulfonates have been used in asymmetric syntheses to selectively O-alkylate alcohols and phenols, typically on a laboratory scale. Aromatic sulfonates are cleaved, ie, desulfonated, by uv radiation to give the parent aromatic compound and a coupling product of the aromatic compound, as shown, where Ar represents an aryl group (18). [Pg.96]

The lack of a second aryl group flanking the active methylene site, however, means that the pX values of the pi val oyl a ceta n il i des tend to be considerably higher than those of the benzoyl acetanilides. As a result, these couplers are rarely used as thek four-equivalent parents. Rather, the coupling... [Pg.476]

It has been shown that cross-coupling reactions constitute a very mild method to introduce different alkyl and aryl groups to the most active C-3 position of the pyrazinone ring [26]. The broadly functionahzed 2-azadiene system of the title compounds was studied in cycloaddition reactions with various electron-reach and electron-poor dienophiles to provide highly substituted heterocycles [24]. [Pg.273]

Alkenylboranes (R2C=CHBZ2 Z — various groups) couple in high yields with vinylic, alkynyl, aryl, benzylic, and allylic halides in the presence of tetra-kis(triphenylphosphine)palladium, Pd(PPh3)4, and a base to give R C CHR. 9-Alkyl-9-BBN compounds (p. 1013) also couple with vinylic and aryl halides " as well as with a-halo ketones, nitriles, and esters.Aryl halides couple with ArB(IR2 ) species with a palladium catalyst. ... [Pg.541]

In a reaction similar to 12-50, azoxy compounds can be prepared by the condensation of a nitroso compound with a hydroxylamine. The position of the oxygen in the final product is determined by the nature of the R groups, not by which R groups came from which starting compound. Both R and R can be alkyl or aryl, but when two different aryl groups are involved, mixtures of azoxy compounds (ArNONAr, ArNONAr, and Ar NONAr ) are obtained and the unsymmetrical product (ArNONAr ) is likely to be formed in the smallest amount. This behavior is probably caused by an equilibration between the starting compounds prior to the actual reaction (ArNO -I- Ar NHOH Ar NO - - ArNHOH). The mechanism has been investigated in the presence of base. Under these conditions both reactants are converted to radical anions, which couple ... [Pg.819]

Attempts to form cyclotrigermanes (and, subsequently, digermenes see Section II.B.l) from the reductive cyclization of diaryldichlorogermanes and lithium naphthalenide (LiNp) with particularly bulky substituents on the aryl groups (i.e., isopropyl) led, instead, directly to the tetraaryldiger-menes by reductive coupling. [Pg.290]

Another group of C—C coupling reactions involve transformations of the acyl function. Thus, Scheme 5 presents simplified patterns for formation of ketones (R = alkyl or aryl group, R = aryl, X = halide). [Pg.222]

The ortho-arylation of 2-arylpyridines with aryltin reagents is mediated by Wilkinson s catalyst. This cross-coupling procedure occurs at high temperatures and consequently, the prevention of double phenylation represents a major hurdle, which is often achieved by adding a methyl group to either the pyridine or aryl group (Equations (125) and (126)).1... [Pg.139]

Preparation of palladium enolates and their reactions (/3-hydride elimination to enones, migratory insertion to C-C multiple bonds, reductive coupling with allyl or aryl groups, etc.) have been reported. However, the nucleophilic addition of palladium enolates to C=0 and C=N bonds has been little investigated.463... [Pg.466]

Ohta s group coupled aryl bromides such as 2-bromonitrobenzene with benzofuran [85]. The heteroaryl Heck reaction took place at the more electron-rich C(2) position of benzofuran. They later described the heteroaryl Heck reactions of chloropyrazines with both furan and benzofuran [86],... [Pg.286]


See other pages where Aryl groups, coupling is mentioned: [Pg.185]    [Pg.220]    [Pg.230]    [Pg.44]    [Pg.38]    [Pg.324]    [Pg.112]    [Pg.534]    [Pg.540]    [Pg.542]    [Pg.938]    [Pg.1657]    [Pg.216]    [Pg.177]    [Pg.176]    [Pg.705]    [Pg.75]    [Pg.142]    [Pg.274]    [Pg.160]    [Pg.308]    [Pg.327]    [Pg.341]    [Pg.353]    [Pg.269]    [Pg.178]    [Pg.273]    [Pg.86]    [Pg.96]    [Pg.124]   
See also in sourсe #XX -- [ Pg.1329 ]

See also in sourсe #XX -- [ Pg.1329 ]

See also in sourсe #XX -- [ Pg.1329 ]




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Aryl coupling

Aryl groups

Coupling of Substituted Glycals with Aryl Groups

Direct Coupling of Glycals with Aryl Groups

Glycals substituted, aryl group coupling

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