Arundo alkaloids

Zhalolov, 1. Z., Khuzhaev, V. U., Levkovich, M. G., Aripova, S. F. and Shashkov, A. S. 2002. Alkaloids of Arundo donax. XL NMR spectroscopic study of the structure of the dimeric alkaloid arundamine. Chemistry of Natural Compounds,... 

Non-isoprenoid Tryptamines.—The structures (21) and (22) have been deduced for donaxarine and donaxaridine, the alkaloids of Arundo donax 14 the relationship between the two is confirmed by the formation of donaxarine by condensation of... 

DMT (dimethyltryptamine nigerine) is an indole alkaloid from Mimosa hostilis, Acacia spp., Arundo donax, Desmodium... 

While Syrian Rue is generally recognized as the best non-rain forest source of harmala alkaloids, DMT sources seem not to be so firmly established. Plants containing DMT are not too hard to find, however. Desmanthus illinoensis (a weed legume common in the midwest), Arundo donax (a bamboo-... 

Gramine (XIII) occurs in barley (59) and the leaves of Arundo donax L. (60). The alkaloid raises blood pressure but does not dilate the rabbit s pupil (61). It causes primary stimulation of isolated uterus and intestines. Administration of large doses results in clonic convulsions and excitation of respiratory center (62). 

Several bisindole alkaloids were isolated from Arundo donax, a perennial giant grass found in Uzbekistan, in addition to the simple bisindoles, arundine (3,3 -diindolylmethane, 125) (77) and ardine (126) (78). 

As an approach to bis(indole) alkaloids finm Arundo donax, Beaudry and co-workers used a ynindole Diels-Alder reaction to construct the core scaffolds. Furan 244 was coupled with indole 245 under copper-mediated conditions in DMSO. Pleating of the resulting product in toluene (sealed tube) furnished the Diels-Alder adduct. Similar skeletons were taken forward to complete the synthesis of arundarine, arundamine, arundanine, and arundacine (14AG(I)11931). 

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