Artemisia lanata

Although the first survey listed 45 natural chlorinated sesquiterpene lactones, several such compounds were omitted in that coverage (1) and are described here. The novel sesquiterpene lactone chlorochrymorin (239) was isolated from Chrysanthemum morfolium (499), and the chlorohydrin graminichlorin (240) is found in Liatris graminifolia (500). The antibacterial AA-57 (241), which is related to pentalenolactone, is produced by a Streptomyces sp. (501). The plant Eupatorium chinense var. simplicifolium has yielded eupachifolin D (242) (502) (side-chain double bond stereochemistry revised (518)), and the new guaianolide andalucin (243) was characterized from Artemisia lanata (503). The previously known chlorohyssopifolins (1) have been studied for cytostatic activity, and the presence of one and even two chlorine atoms amplifies this activity (504). 

Aguilar JM, Collado IG, Macias FA, Massanet GM, Rodriguez-Luis F, Fronczek FR, Waikins SF (1988) Sesquiterpene Lactones from Artemisia lanata. Phytochemistry 27 ... 

Fig. 98.2 Guaianolides isolated from plants belonging to Asteraceae (3-8, 12) and Apiaceae (9-12). Compound 3 matricin fmm Matricaria chamomilla [2], 4 mpicolin A 8-0-acetate from Artemisia tripartita [2], 5 from Lasiolaena morii [9], 6 from Artemisia xanthochroa [10], 7 bacchariolide from Baccharis salicina [11], 8 cichopumolide from Cichorium pumilum [12], 9 from Hymenoxys scaposa var. villosa [13], 10 from Laser trilobum [14], 11 thapsigargin from Thapsia garganica [15], and 12 carmenin fromFerula sp. (Apiaceae) [16, 17] and from Artemisia lanata (Asteraceae) [18]...

Atriplex confertifolia, Eurotia lanata, Artemisia tridentata... 

---