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Arsenite Resistance in Leishmania

Arsenite Resistance in Leishmania and Possible Drug Targets... [Pg.1]

In conclusion, above studies provide valuable insights into multifactorial nature of oxyanion (arsenite) resistance in Leishmania. Several metabolic pathways and membrane transporters are implicated in the resistance phenotype. A recent report utilizing transcript profiling of arsenite... [Pg.5]

Grondin K, Papadopoulou B, Ouellette M. Homologous recombination between direct repeats sequences yields P-glycoptotein containit circular amplicons in arsenite resistant Leishmania. Nucleic... [Pg.6]

Singh AK, Liu HY, Lee ST. Atomic absorpdon spectrophotometric measurement of intracellular arsenite in arsenite-resistant Leishmania. Mol Biochem Parasitol 1994 66 161-164. [Pg.7]

Kaut J, Dey CS. Putative P-glycoprotein expression in arsenite-resistant Leishmania donovani down-regulated by verapamil. Biochem Biophys Res Commun 2000 271 615-619. [Pg.7]

Lin YC, Hsu JY, Chiang SC et al. Distinct overexpression of cytosolic and mitochondrial tryparedoxin peroxidases results in preferential detoxification of different oxidants in arsenite-resistant Leishmania amazonensis with and without DNA amplification. Mol Biochem Parasitol 2005 142 66-75. [Pg.7]

Prasad V, Kumar SS, Dey CS. Resistance to arsenite modulates levels of alpha-tubulin and sensitivity to paclitaxel in Leishmania donovani. Parasitol Res 2000 86 838-842. [Pg.7]

Prasad V, Dey CS. Tubulin is hyperphosphorylated on serine and tyrosine residues in arsenite-resistant Leishmania donovani promastigotes. Parasitol Res 2000 86 876-880. [Pg.7]

Jayanarayan KG, Dey CS. Altered expression, polymerisation and cellular distribution of alpha-/ beta-tubulins and apoptosis-like cell death in arsenite resistant Leishmania donovani promastigotes. Int J Parasitol 2004 34 915-925. [Pg.7]

Jayanarayan KG, Dey CS. Altered tubulin dynamics, localization and post-translational modifications in sodium arsenite resistant Leishmania donovani in response to paclitaxel, trifluralin and a combination of both and induaion of apoptosis-like cell death. Parasitology 2005 131 215-230. [Pg.7]

Lee ST, Liu HY, Lee SP et al. Sdection for arsenite resistance causes reversible changes in minicirde composition and kinetoplast oi anization in Leishmania mexicana. Mol Cdl Biol 1994 14 587-596. [Pg.8]

Jayanarayan KG, Dey CS. Overexpression and inaeased DNA topoisomerase Il-like enzyme activity in arsenite resistant Leishmania donovani. Microbiol Res 2003 158 55-58. [Pg.8]

Singh G, Jayanarayan KG, Dey CS. Novobiocin induces apoptosis-like cdl death in topoisomerase II over-expressing arsenite resistant Leishmania donovani. Mol Biochem Parasitol 2005 141 57-69. [Pg.8]

See other pages where Arsenite Resistance in Leishmania is mentioned: [Pg.1]    [Pg.192]    [Pg.332]    [Pg.2]    [Pg.3]    [Pg.5]    [Pg.5]    [Pg.7]    [Pg.2]    [Pg.2]   


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