Army worm cells

Baculoviruses are members of a large group of double-stranded DNA viruses which only infect invertebrates, including insects. The restricted host range makes baculoviruses safer than mammalian expression systems. The most widely used baculoviruses are Autographa califor-nica nuclear polyhedrosis virus and the Bombyx mori nuclear polyhedrosis virus. The host cell most commonly used is Sf9, derived from the fall army worm Spodoptera frugiperda. 

Cells derived from the ovary of the fall army worm Spodopterafrugiperda are the most common used cell lines for heterologous protein production with a baculovirus vector (see Table l),but some authors have reported the use of a different cell line for VLP production, Trichoplusia ni HighFive cells (Invitrogen, San Diego, US) [24,41,50]. 

Mitsui, T., Tada, M., Nobusawa, C., and Yamaguchi, I., Inhibition of UDP-N-acetylglucosamine transport by diflubenzuron across biomembranes of the midgut epithelial cells in the cabbage army worm, Mamestra brassicae L., /. Pestic. Science, 10,55,1985. 

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