Aristolochic acids sodium salts

SYNS ARISTOLOCHIC ACID, SODIUM SALT ARISTOLOCHIC ACID I SODIUM SALT 8-METHOXY-6-NITROPHENANTHRO(3,4-D)-l,3-DIOXOLE-5-CARBOXYLIC ACID SODIUM SALT PHEN-ANTHRO(3,4-D)-l,3-DIOXOLE-5-CARBOXYUC ACID, 8-METHOXY-6-NITRO-, SODIUM SALT... 

Over the last seventy years over sixty species of Aristolochia have been exploited for chemical examination by research groups throughout the world and a variety of compounds have been isolated. The spectrum of physiologically-active metabolites from Aristolochia species covers 14 major groups based on structure aristolochic acid derivatives, aporphines, amides, benzylisoquinolines, isoquinolones, chlorophylls, terpenoids, lignans, biphenyl ethers, flavonoids, tetralones, benzenoids, steroids, and miscellaneous. The aristolochic acid derivatives, host of phenanthrene derived metabolites were further classified into aristolochic acids, sodium salts of aristolochic acids, aristolochic acid alkyl esters, sesqui- and diterpenoid esters of aristolochic acids, aristolactams, denitroaristolochic acids, and aristolactones. The terpenoids can further be subdivided into 4 groups mono-, sesqui-, di- and tetraterpenoids. 

It is interesting to note that Formosan Aristolochia species including A. cucurbitifolia, A. foveolata, A. heterophylla, A. kaempferi and A. zollingeriana are the only species [159,228,244-246] from which sodium salts of aristolochic acids were isolated. However, very recently Lopes and co workers have also isolated sodium aristolochate I (21), II (18), Ilia (19) and IVa (22) from Brazilian species, A. pubescens [208], Isolates of this class from various Aristolochia species were listed in Table 4. 

Table 4. Sodium Salts of Aristolochic Acids Isolated from Aristolochia Species...

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