Aripiprazole nervous system

An overdose of 195 mg (17.1 mg/kg) of aripiprazole in a 2.5 year-old child caused nervous system depression that did not require respiratory support but persisted for almost 2 weeks, because of the long half-life of aripiprazole there were no significant cardiovascular effects (18). 

Nervous system Extrapyramidal reactions to aripiprazole have been described [SEDA-31, 75 SEDA-32,93 SEDA-33,101] and further cases emphasize the need for caution when treating patients with aripiprazole. 

Wei C Yinqiao Pian, 771 nervousness bofutsushosan, 774 Ephedra, 11A liraglutide, 693 nervous system depression chloroform, 195 prilocaine, 216 rupatadine, 274-5 neural tube defects caffeine, 6-7 neurodevelopment delay amiodarone, 294 neuroexdtation pethidine (meperidine), 151 neuroleptic malignant syndrome aripiprazole, 61 lithium, 27... 

Nervous system Aripiprazole has been previously associated with neuroleptic malignant syndrome but with doubts about the validity of the diagnoses. However, postmarketing pharmacovigilance schemes in Australia have collected a higher proportion of cases of neuroleptic malignant syndrome with aripiprazole compared with the total number of reports received for... 

Nervous system Neuroleptic malignant syndrome is described with aripiprazole in an adolescent with a history of impulsive, disorganised and bizarre behaviour [91 ]. 

Nervous system TD is less commonly associated with SGAs but certain factors may increase risk. A case of an adolescent female with mental retardation and schizophrenia use developing TD with chronic use of olanzapine is reported [168 ]. This patient was subsequently successfully treated with clozapine. Similarly, the presence of Dandy-Walker variant likely predisposed a 20-year-old male to TD which had first developed on FGAs and exacerbated with olanzapine before improving on low-dose aripiprazole [169 ]. A case of a 24-year-old male who developed TD after reinstatement of olanzapine and a course of ECT is reported [170 ]. 

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