Arginine Glutamate

Therapeutic Function Ammonia detoxicant (hepatic failure) 

Chemical Name Glutamic Acid Compound with L-Arginine Common Name — 

H2NC(NH)HN(CH2)3CH(NH2)C00H-H00C(CH2)2(NH2)C00H Chemical Abstracts Registry No. 4320-30-3 

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Figure 30-3. Top Catabolism of proline. Numerals indicate sites of the metabolic defects in type I and type II hyper-prolinemias. Bottom Catabolism of arginine. Glutamate-y-semialdehyde forms a-ketoglutarate as shown above. , site of the metabolic defect in hyperargininemia.

Arginine, glutamic acid, lysine, methionine, phenylalanine, serine, phenylglycine lOmM H2S04/Me0H (20/80) 260... 

Amino acids that are converted Arginine glutamate... 

Arginine, glutamate, glutamine, histidine, and proline produce a-ketoglutarate isoleucine, methionine, threonine, and valine produce succinyl-CoA four carbon atoms of... 

On binding to the Cdk, the a5 helix of cyclin A re-orients the PSTAIRE helix of Cdkl, opening the active site cleft. (PSTAIRE is proline, serine, threonine, alanine, isoleucine, arginine, glutamic acid). 

An interesting recent development is the use of arginine-glutamate salt (typically 50 mmol l-1 L-arginine + 50 mmol l-1 L-glutamate) for NMR studies of proteins using CC probes. This zwitterionic salt not only has much lower conductivity than NaCl but has also been shown to help solubilize proteins that are prone to aggregation.9,10... 

Yamamoto RS, Weisburger JH. 1970. Failure to arginine glutamate to inhibit lung tumor formation by isoniazid and hydrazine in mice. Life Sci 9 285-289. 

Arginine Glutamate. Glsttntic acid amtpd with... 

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