Are Extremely Varied in Their Specificities

As information on antibody sequences has accumulated, it has become increasingly clear that within the V regions of both the heavy and light chains, three segments 

Complement fixation placental transfer stimulation of ingestion by macrophages 

Antibody Diversity Is Augmented by Unique Genetic Mechanisms 

Antibodies have been studied most extensively in the mouse, an ideal vertebrate for both genetic and biochemical manipulations. It is believed that mice can synthesize more than a million antibodies with different antigenic specificities. This enormous diversity of proteins is generated from a limited amount of genetic information with the help of two mechanisms Somatic recombination and somatic mutation. 

These results strongly suggested that at some point during development from the embryonic state, a rearrange- 

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