Applications of Protein Characterization with Mass Spectrometry Proteomics

Applications of Protein Characterization with Mass Spectrometry Proteomics 

The ability to sequence proteins at low levels and sometimes in a high throughput fashion has considerably advanced protein-oriented molecular biological research. The qualitative change affects the two criteria sensitivity and throughput. 

Novel mass spectrometric techniques were used to increase the sensitivity by a factor of 50 to 100 compared with conventional methods. This made proteins accessible that can be purified only in minute amounts (Lingner et al., 1997). 

The purpose of targeted proteomics is to explore the function of proteins by studying their physical relationship to other proteins. 

These efforts are characterized by a specific protein purification method. The aim of the investigation is to find the molecules involved 

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V. Applications of Protein Characterization with Mass Spectrometry Proteomics... 

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