Applications in Pharmacy

Types of Nanomaterials Characteristics Applications in Pharmacy References... 

APPLICATIONS IN PHARMACY, PHARMACEUTICAL CHEMISTRY AND PHARMACOLOGY Possible applications and recent developments Polarographic activity of pharmaceuticals... 

Surface activity is a phenomenon that has widespread consequences. Surface-active substances are those which adsorb at surfaces and lower surface tension these so-called surfactant materials have a wide applicability in pharmacy. In micellar form they can solubilise water-insoluble dmgs and many at low concentrations can increase membrane permeability and aid the transport of dmgs across biological barriers. Many dmgs have surface-active properties and this might have consequences for their activity and behaviour. The topic is summarised in a chapter on surface activity and surfactants. 

In recent years, new biological roles have been ascribed to HA along with its essential function as a component of ECM. Due to its unique rheological properties, hyaluronan has found many applications in pharmacy and medicine. Since it has been reported that biological effects of HA depend on its molar mass, methods of... 

Solid phase extraction (SPE) was developed during the last 10 years as an effective analytical tool for the isolation and purification of a wide range of compounds. For many applications in pharmacy and biomedicine, it is playing an increasingly important part in sample preparation both for trace concentrations and for the isolation of substances on a preparative scale [20]. 

Izmailov, N.A., Shreiber, M.S. (1938) Spot chromatographic adsorption analysis and its application in pharmacy communication I. Farmatsiya, 3, 1-7 (in Russian translation into Enghsh by Berezkin, V. (1995) m. Journal of Planar Chromatography, 8,402-405). 

In 1938, N. A. Ismailov and M. S. Shraiber [313] described the basic principle of the procedure in an article entitled Analysis by Drop-chromatography and its Application in Pharmacy . They applied the method to the separation and characterisation of extracts of medicinal plants (tinctures of the Soviet Pharmacopoeia VII). 

Runkana V, Somasundaran P (2007) Mathematical modeling of coagulation and flocculation of colloidal suspensions incorporating the influence of surface forces. In Colloid stability and application in pharmacy. Colloid and interface science series, vol 3. Wiley-VCH, Weinheim... 

Despite the above-mentioned advantages of multiple emulsions, progress on commercial application in pharmacy has been slow for the following reasons The complex nature of the system, which may require a carefully designed two step preparation. Limited availability of surfactants that can be used in preparation of the essential two emulsions, e.g. for a W/O/W systems one has to start by preparing a W/0 emulsion, which is then further emulsified into water to produce the W/O/W drops (two surfactants with low and high HLB numbers are required). 

Lyklema, J. and Leermakers, F.A.M. (2007) Ion specificity in colloidal systems (ed. Th.R. Tadros), Ch 8 Colloid Stability and Application in Pharmacy, Vol 3, Wiley-VCH Verlag GmbH. 

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