Aporphine alkaloids names

These domino reactions have also been employed by us for the total synthesis of pharmacologically important [50,51] aporphine alkaloids namely dehydronomuciferine (1) and ( ) N-nomuciferine (2)(Scheme 1), and biologically active [52] phenanthrene alkaloids namely N-noratherosperminine (3) and atherosperminine (4)(Scheme 2). Incidentally, phenanthrene alkaloids are related to the aporphines, from which they can be obtained by degradative procedures [37],... 

The year under review has witnessed the isolation and structural elucidation of no less than nine new aporphines, as well as of five aporphine-benzylisoquinoline dimers. Two of these five aporphine-benzylisoquinolines, namely kalashine and khyberine, are the first such dimers known to be substituted at C-l 1 of the aporphine moiety. Thallium(m) trifluoroacetate is an oxidizing agent which effects the cyclization of tetrahydrobenzylisoquinolines to aporphines in satisfactory yields.1 A listing of aporphinoid alkaloids has appeared.2... 

Dioxoaporphines constitute a relatively small group of aporphine alkaloids. Three 4,5-dioxoaporphines, namely, artabotrine (50), 8-methoxy-ouregidione (51), and ouregidione (52), have been isolated from the stem bark of Artabotrys zeylanicus (Annonaceae) (48,49). The structure of... 

Alkaloids of the Anonace. This botanical family belongs to the natural order Anonales, which is nearly related to the Laurales, in which are included the families Lauraeeas and Monimiaeeas. It is not surprising, therefore, that the characteristic alkaloids found in these families are of one type, namely derivatives of aporphine. 

This is a 1,1-spirobenzyl intermediate to what is quite likely the entire family of the aporphines. The "pro" part of the name suggests that this is a biosynthetic precursor to these alkaloids. Very often there is a keto function at the 4-position of the benzyl group (equivalent to a hydroxyl group on the original benzyl), to facilitate the spiro loss of aromaticity needed to achieve this type of coupling. This is directly analogous to the (2,4a) attacks needed to get into the morphinans, where... 

A careful investigation of the alkaloidal content of the Brazilian plant Ocotea minarum (Lauraceae) has led to five new aporphines, namely ocotominarine (3), ocominarine (4), norleucoxylonine (5), iso-oconovine (6), and 4-hydroxy-dicentrine (7).4... 

The alkaloids in the leaves of this plant consisted largely of isocrydine and two new aporphines, namely, 10-hydroxy-l,2-(methylenedioxy)-aporphine and 2,ll-dihydroxy-l,10-dimethoxyaporphine. The bark yielded predominantly laurolitsine (160a). 

Coiydalis alkaloids. General name for a series of iso-quinoline alkaloids with aporphine, protoberberine, or benzo[c]phenanthridine skeletons tom the roots of the yellow fumitory and some other Corydalis species (see aporphine, protoberberine, and benzo[c]phenanthri-dine alkaloids). Some of the C.a. have narcotic, muscle paralyzing activities and the powdered root stocks of the C. a.-containing plants had traditional use as anthelmintic and menstruation-promoting agents. 

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