Antitarget screening

In conclusion, the 3D pharmacophore and QSAR models presented can be easily used for in silico antitarget screening of compound databases to identify ligands with side affinity and potential al-mediated side effects. 

Validation of Antitarget Pharmacophore Models 6.3.3.1 Virtual Screening Hit Rates and Yields... 

Receptorome Screening to Identify Drug Targets and Antitargets... 

In this work, we will try to illustrate, among the large variety of approaches and procedures proposed at different levels of complexity and sophistication, the most relevant methods and results obtained from different authors on computational modeling of both selective antagonism at oq-ARs and their side affinity propensity (antitarget modeling and screening). 

It isn t always easy to know which targets to avoid, but the most important antitargets do need to be identified somehow, if only by educated guesses or literature reports of toxicity associated with them, so that compounds can be routinely screened against them as early as possible. 

Important antitargets need to be identified early on and screened against... 

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