Antiplatelet agents nitrates

NITRATES ANTIPLATELET AGENTS-ASPIRIN 1 antihypertensive effect with aspirin effect not noted with low-dose aspirin Aspirin may cause sodium retention and vasoconstriction at possibly both renal and endothelial sites Monitor BP at least weekly until stable... 

The pharmacological treatment options for ACS include agents that either reduce oxygen demand (beta blockers) or increase oxygen supply (nitrates, potassium channel activators, calcium channel blockers) to the heart and antiplatelet (aspirin, ADP-receptor antagonists, GPIIb/llla receptor blockers) and antithrombin therapy (unfractionated heparin, low molecular weight heparin, direct thrombin inhibitors) (10). 

Treatment of the patient in the earliest stages of Ml is preferable. In any case, treatment must follow standard of care and address issues that are potentially life-threatening first. Use of oxygen, morphine, nitrates, recanalization of the vessels with clot-reduction medications or mechanical means, and aspirin or antiplatelet aggregation agents underscores some of the most basic pharmacologic approaches. Issues of hypertension must be addressed pharmacologically. 

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