Antimony amino derivatives

Mercury Derivatives.—The mode of preparation of these compounds is similar to that adopted for the preceding compounds. When mercuric chloride is used and the operations are carried out in methyl alcohol, a yellow powder results, which is soluble in methyl alcohol, glycerine, ethylene glycol, and acidified potassium iodide solution. It is decomposed by water or sodiunr hydroxide aird is only slightly soluble in dilute acids, but if treated with antimony compounds, antimonyl derivatives are obtained, which are more soluble and are stable in alkaline solutions. The decomposition by water is said to give rise to colloidal mercury and 3-amino-4-hydroxyplienylarsenoxide, OH.CgHa.(NH2).AsO. If an excess of mercuric chloride is used, the oxidation proceeds to o-aminophenol, mercurous chloride, and arsenious... 

Few medicines based on boron are known, in general boric acid or a boronic acid serve to esterify an a-diol or an o-diphenol. This is the case for the emetic antimony borotartrates of the ancient pharmacopoeias, for the injectable catecholamine solutions, for tolboxane, which is close to meprobamate and which was commercially available as a tranquillizer some decades ago, and also for the phenylboronic esters of chloramphenicol. Boro-mycine was the first natural product containing boron. It is a complex between boric acid and a polyhydroxylated tetradentate macrocycle. Some boronic analogues of amino acids were prepared as chymotrypsine and elastase inhibitors. The most important medical use of derivatives of boron derivatives is the treatment of some tumours by neutron capture therapy, " the problem here being to ensure a sufficient concentration of the product in the tumour being treated. 

Amino-4-hydroxyphenylarsine also reacts with potassium anti-monyl tartrate m aqueous alkali solution to form a dark brown arsenic-antimony compound, soluble m acid or alkali A This body yields a N-hydroxyhenzylidene derivative when shaken with salicyl aldehyde. 

Titanium, tetrakis(trimethysilyl)oxy-, 334 Titanium complexes alloy hydrides, 353 amino adds, 342 antimony, 345 arsenic, 345 bromides, 357 chlorides, 355, 356 fluorides, 354 Group IV derivatives, 352 halides, 354 electron spectra, 358 hexamethylphosphoramide, 335 iodides, 357... 

By contrasL with alkoxides of niobium, tantalum, germanium, tin, and antimony both the hydroxylic and the amino group protons of ethanolamine undergo replacement reactions to form cyclic derivatives (Eq. 2.206) ... 

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