Antimicrobial single-dose therapy

Much of the use of antimicrobial agents is irrational. Antimicrobial therapy for superficial wounds and single doses of penicillin administered after the elective castration of normal horses has no real therapeutic benefit and encourages antimicrobial resistance. 

These extended case studies complement the basic information presented in Chapters 1 to 40. They reinforce basic principles of pharmacology, such as the role of patient factors in empiric antimicrobial therapy Most of the cases provide clinical information obtained from a single patient some cases describe a composite of typical features derived from several patients. These cases illustrate simple pharmacologic principles, such as consideration of kidney function in drug dosing—concepts useful in answering examination questions, and in the clinics. 

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