Ligand antigen

Antibody, an antibody made by certain white blood cells in response to a foreign substance (antigen) is an immunological protein which binds to a specific antigen (ligand). 

Antibody An immunoglobulin that will bind with an antigen (ligand or hapten) or immunogen ... 

To develop the endothelium, provision must be made for attachment of the cells. This attachment can be accomplished by connection to a fibrin capsule, physical attachment to a rough surface (as in a bundle of fibers) or via adsorbed or covalently bonded antigen ligands. We will expand on these concepts (development of endothelium and antithrombic hydrophilic polymers), but it is useful to mention that both strategies are possible with properly formulated polyurethanes. Nonthrombic polyurethanes can conceivably be devised by hydrophilic polyurethanes or by the attachment 2005 by CRC Press LLC... 

Purification of IgG Using Affinity Chromatography on Antigen Ligand or Protein A/G Columns... 

Page, M. and Thorpe. R. (1996) Purification of IgG using affinity chromatography on antigen-ligand columns, in The Protein Protocols Handbook. (Walker, J. M., ed.) Humana Press, Totowa, NJ, pp. 739-741. 

Lymphocyte-specific protein tyrosine kinase Lymphocyte function-associated antigen Ligand-gated ion channel Luteinizing hormone Laser-induced fluorescence... 

Haynes, J. D., Dalton, J. 1, Klotz, F. W., McGinnis M. H., Hadley, T. J., Hudson, D. E., and Miller, L. H. (1988). Receptor-like specificity of a Plasmodium knowlesi malarial protein that binds to Duffy antigen ligands on erythrocytes.. Exp. Med. 767,1673-1881. 

Four possible mechanisms for solid-state extraction (a) adsorption onto a solid substrate (b) absorption into a thin polymer or chemical film coated on a solid substrate (c) metal-ligand complexation in which the ligand is covalently bound to the solid substrate and (d) antibody-antigen binding in which the receptor is covalently bound to the solid substrate. 

The largest numbers of integrins are members of the (31 integrins, also known as the very late antigen (VLA) subfamily because of its late appearance after activation. There are at least seven receptors characterized from this subfamily, each with different ligand specificity. Among the most studied include the 04(31 and a5 31 receptors. The leukocyte integrin a4 31 is a cell adhesion receptor that is predominantly expressed on lymphocytes, monocytes and eosinophils. 

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