Antibody thiamin deficiency

In confirmation of previous findings, these studies have emphasized the failure of inanition to modify the antibody response. The lack of correlation between growth inhibition and suppression of antibody response was again apparent. This was strikingly evidenced in the thiamine and folic acid deficiencies. Thus, despite the more marked growth-inhibitory effect of the thiamine deficiency, the antibody response of the thiamine-deficient rats was much greater than that of the folic acid-deficient animals. 

Axelrod, A. E, and Hopper, S. (1960) Effects of pantothenic acid, pyridoxine and thiamine deficiencies upon antibody formation to influenza virus PR-8 in rats, J. Nutr., 72 325. 

Kumar, M., anT Axelrod, A.E. (1978). Cellular antibody synthesis in thiamin, riboflavin, biotin and folic acid-deficient rats. Proc. Soc. Exp. Biol. Med. 157 421-423. 

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