Antiasthmatics, other

Agent for Chronic Obstructive Agent for Transplant Rejection Antihypertensive Agent for Rhinitis I mm unosu ppressant Antidepressant Ophthalmic Agent Antiallergic/Antiasthmatic Other... 

Other Pharmaceuticals. Other pharmaceutical products incorporating the thiophene ring include the antiasthmatic dmg Ketotifen [34580-13-7] (Sandoz) (53), which is particularly marketed in Japan. The antifungal dmg Tioconazole [65899-73-2] (Pfizer) (54) is based on... 

Cromolyn Sodium (Intal, NasalCrom, Opticrom, Others) [Antiasthmatic/Mast Cell Stabilizer] Uses "Adjunct to the Rx of... 

Other more complex examples are known,156-167 of which some are tranquillizing, antiasthmatic, or analgesic.I56,I57J6S The parent triazolo-[4,5-b]pyridine 4 has also been made from 1,2-diaminopyridine with N-nitrosodiphenylamine.168 If N-substituted diaminopyridines are used, N-sub-stituted triazolopyridines can be obtained.I53,169 l8° Examples are provided by... 

Applications of the Conrad-Limpach reaction to the synthesis of 1-hydroxy-4,7-phenanthrolines or, more correctly, l-oxo-l,4-dihydro-4,7-phenanthrolines, from p-phenylenediamine or 6-aminoquinolines continue to be reported. l,10-Dihydroxy-3,8-dimethyl-4,7-phenanthroline has again been prepared from p-phenylenediamine,234 hot diphenyl ether being used to effect the cyclization. Other examples include the new or improved preparations of l-hydroxy-3-methyl-, 10-amino-l-hydroxy-3-methyl-,232 2-(y-chlorocrotonyl)- l,10-dihydroxy-3,8-dimethyl-, and 2,9-bis (y- chlorocrotonyl)-1,10- dihydroxy - 3,8 - dimethyl - 4,7 - phenanthro-lines.235 Compounds prepared in this way have been patented as antiasthmatic agents.178 A closely related synthesis employing poly-phosphoric acid as cyclizing agent has yielded l-hydroxy-3-phenyl-4,7-phenanthroline.236... 

Other derivatives of 4,7-phenanthroline have been patented as antibacterial and antifungal agents238,272 and as antiasthmatic agents.178... 

Epinephrine (Adrenalin, Bronkaid Mist, Primatene Mist, others). Epinephrine appears to directly stimulate all adrenergic receptor subtypes and is administered for a variety of reasons. Epinephrine is found in many antiasthmatic inhalation products because of its ability to stimulate beta-2 receptors on the bronchi. Because it stimulates vascular alpha-1 receptors, epinephrine may be applied topically to produce local vasoconstriction and control bleeding during minor surgical procedures (e.g., suturing superficial wounds). Likewise, epinephrine may be mixed with a local anes-... 

ANTIASTHMATIC AGENTS relieve the symptoms of bronchial asthma or prevent recurrent attacks. The symptoms of asthma include bronchoconstriction (obstructive airways disease), often with over-secretion of fluid within the bronchioles and other breathing difFiculties. Two main types of drugs are used the first to treat acute attacks and the second as prophylactics to prevent attacks... 

FACTOR RECEPTOR ANTAGONIST. It is an ANTIASTHMATIC and has Other activities. BN 52063 is a mixture of ginkgolides and has a similar type of activity. 

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