Anti-neoplastic disorders

Platinum Dichlorodiammine Platosin — anti-neoplastic disorders... 

Furthermore, the identification of compounds in medicirral plant extracts with potential NF-kB inhibitory activity and/or inhibitory effects on targets of the inflammatory/apoptotic cascade might lead to the development of new anti-irtflammatory, immunomodulatory, or apoptotic drugs for clinical and endemic trse. These norrsteroidal modulators may serve as lead compounds for developing new pharmaceuticals to be used in the treatment of inflammatory diseases, hormonal disturbances, cancer, or conditions associated with an increased activity of the trarrscription factor NFkB. In conclusion, kurarinone holds promise as a prophylactic compound that may have beneficial effects in the treatment of various postmenopausal disturbances and neoplastic disorders. 

Acquired von Willebrand disease is a rare bleeding disorder that is similar to the congenital form of the disease. It has been reported primarily in association with autoimmune disorders, such as systemic lupus erythematosus, lymphoproliferative disorders, and neoplastic disease. Certain medications also have been associated with acquired von Willebrand disease, including valproic acid, dextran, and ciprofloxacin. Bleeding manifestations vary frommild to severe, and the condition often resolves with treatment of the underlying disease. In the acquired disease, von Wfllebrand factor appears to be synthesized in normal amounts, but then is rapidly removed from plasma by anti-von Willebrand factor antibodies, adsorption to tumor cells, or other mechanisms. ... 

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