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Anti-ganglioside antibodies

Pathogenic Anti-Ganglioside Antibodies and C. jejuni Ganglioside Mimicry... [Pg.227]

Keywords Acute flaccid paralysis Anti-ganglioside antibodies Campylobacter jejuni Experimental allergic/autoimmune neurids (BAN) Gangliosides Immune neuropathies Molecular mimicry T-cells... [Pg.263]

A brief discussion of peripheral nerve gangliosides is necessary for understanding the pathogenetic effects of anti-ganglioside antibodies. Gangliosides, the target antigens of... [Pg.270]

With this background information, we outline the experimental data that supports the notion that anti-ganglioside antibodies can induce nerve fiber injury in animal models and briefly review the effects of these antibodies on nodes of Ranvier and motor nerve terminals. Two animal models that provide proof of concept that anti-ganglioside antibocUes with -GMl and -GDla specificities can induce neuropathy. [Pg.271]

Paparounas K, O Hanlon GM, O Leary CP, Rowan EG, Willison HJ (1999) Anti-ganglioside antibodies can bind peripheral nerve nodes of Ranvier and activale the complement cascade without inducing acute conduction block in vitro (see comments). Brain 122 807-816. [Pg.279]

The effects of anti-ganglioside antibody-mediated injury on motor nerve terminals have been extensively examined by in vitro phrenic nerve-diaphragm preparations. Current... [Pg.271]

Sheikh KA, Zhang G, Gong Y, Schnaar RL, Griffin JW (2004) An anti-ganglioside antibody-secreting hybridoma induces neuropathy in mice. Ann Neurol 56 228-239. [Pg.280]

Schwarz A, Futerman AH (1996) The localization of gangliosides in neurons of the central nervous system the use of anti-ganglioside antibodies. Biochim Biophys Acta 1286 247-267... [Pg.1688]

See other pages where Anti-ganglioside antibodies is mentioned: [Pg.212]    [Pg.227]    [Pg.227]    [Pg.227]    [Pg.228]    [Pg.228]    [Pg.229]    [Pg.230]    [Pg.231]    [Pg.265]    [Pg.267]    [Pg.269]    [Pg.270]    [Pg.271]    [Pg.272]    [Pg.272]    [Pg.274]    [Pg.321]    [Pg.767]    [Pg.265]    [Pg.267]    [Pg.269]    [Pg.270]    [Pg.271]    [Pg.271]    [Pg.271]    [Pg.272]    [Pg.272]    [Pg.274]    [Pg.274]    [Pg.274]    [Pg.274]    [Pg.321]    [Pg.767]   
See also in sourсe #XX -- [ Pg.212 , Pg.227 , Pg.228 , Pg.229 , Pg.230 ]

See also in sourсe #XX -- [ Pg.269 , Pg.270 , Pg.272 ]

See also in sourсe #XX -- [ Pg.269 , Pg.270 , Pg.271 ]



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