Interactions antagonistic

A. Miklavc, D. Kocjan, J. Mavri, J. Roller and D. Hadzi, On the fundamental difference in thermodynamics of agonist and antagonist interactions with P-adrenergic receptors and the mechanism of entropy-driven binding. Biochem. Pharmacol., 40 (1990) 663-669. 

Ferre, S., O Connor, W. T., Snaprud, P., Ungerstedt, U. and Fuxe, K. Antagonistic interaction between adenosine... 

Semighini CP, Hornby JM, Dumitru R, Mckerson KW, Harris SD, Farnesol-induced apoptosis in Aspergillus nidulans reveals a possible mechanism for antagonistic interactions between fungi, Mol Microbiol 59 753-764, 2006. 

Savelev S, Okello E, Perry NSL, Synergistic and antagonistic interactions of anticholinesterase terpenoids in Salvia lavandulaefolia essential oil, Pharmacol Biochem Behavior 75.SSI—66S, 2003. 

The wide variation in structure, ranging from complex steroids to the inert monatomic gas xenon, led to several theories of anesthetic action. The mechanism by which inhalation anesthetics manifest their effect is not exactly known. Since they do not belong to one chemical class of compounds, the correlations between structure and activity are also not known. Inhalation anesthetics are nonspecific and therefore there are not specific antagonists. Interaction of inhalation anesthetics with cellular structures can only be described as van der Waals interactions. There are a number of hypotheses that have been advanced to explain the action of inhalation anesthetics however, none of them can adequately describe the entire spectrum of effects caused by inhalation anesthetics. 

Buspirone does not appear to have a major effect on the BZ-GABA-chloride ionophore complex and, if anything, has some antagonistic interactions with GA-BAergic transmission (although it does not induce seizures) (Jann, 1988 Baldessarini, 1996). The lack of GABAergic effects is evident in the fact that buspirone does not consistently cause sedation, it is not a muscle relaxant, it is not an anticonvulsant, and it does not relieve BZ withdrawal (Jann, 1988 Cole and Yonkers, 1995). 

Dickenson, A. H. NMDA receptor antagonists interactions with opioids, Acta Anaesthesiol. Scand. 1997, 41, 112-115. 

Gomez AR, Garcia Calvo M, Vasquez 1, Marvizon CG, Valdiviero T, Major F (1989) Thermodynamics of agonist and antagonist interaction with the strychnine-sensitive glycine receptor. J Neurochem 52(6) 1775-1780... 

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