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3 Adrenergic receptor antagonist interactions

Ferry, D.G. Caplan, N.B. Cubeddu, L.X. Interaction between antidepressants and alpha 1-adrenergic receptor antagonists on the binding to alpha 1-acid glycoprotein. J.Pharm.Sci., 1986, 75, 146—149... [Pg.533]

Characterization of the allosteric interactions between antagonists and amiloride at the human ajA-adrenergic receptor. Mol. Pharmacol. 53 916-925. [Pg.78]

A. Miklavc, D. Kocjan, J. Mavri, J. Roller and D. Hadzi, On the fundamental difference in thermodynamics of agonist and antagonist interactions with P-adrenergic receptors and the mechanism of entropy-driven binding. Biochem. Pharmacol., 40 (1990) 663-669. [Pg.417]

Weiland GA, Minneman KP, Molinoff PB (1979) Fundamental difference between the molecular interactions of agonists and antagonists with the beta-adrenergic receptor. Nature 281(5727) 114-117... [Pg.48]

Figure 13.5 Topographical interaction model of ana adrenergic receptor generated based on public site-directed mutagenesis. Both pharmacophore models have been mapped into the topographical model of the receptor. The model reveals putative receptor interaction sites for most of the pharmacophoric features observed within each antagonist class, (a) Class I pharmacophore with prazosin as reference compound (b) class II pharmacophore with compound 10 as reference. Pharmacophoric features are red for posi-... Figure 13.5 Topographical interaction model of ana adrenergic receptor generated based on public site-directed mutagenesis. Both pharmacophore models have been mapped into the topographical model of the receptor. The model reveals putative receptor interaction sites for most of the pharmacophoric features observed within each antagonist class, (a) Class I pharmacophore with prazosin as reference compound (b) class II pharmacophore with compound 10 as reference. Pharmacophoric features are red for posi-...
The bovine parathyroid gland also possesses an alpha-adrenergic receptor (16). However, it seems improbable that an interaction between dopamine and the alpha-adrenergic receptor accounts for the physiological and biochemical effects of dopamine upon this tissue. Phentolamine, an alpha-adrenergic antagonist, has no effect on... [Pg.11]

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See also in sourсe #XX -- [ Pg.186 , Pg.548 ]



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Adrenergic antagonists

Adrenergic receptor antagonists

Adrenergic receptors receptor

Antagonistic interactions

Receptor interaction

Receptors 3-adrenergic

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