Anions synergistic, characteristics

Gillissen [104] finds that the antibacterial action of tyrothricin is influenced by the presence of solubilizers. Cationic surfactants have a synergistic effect (as mentioned above) on its activity against Gram-positive and Gram-negative bacteria, whereas polysorbate 80 inhibits its activity. It is thus important that these effects are borne in mind, and a compromise must be found between the stability and incompatibility characteristics of the solution and the activity of the product. The complexity of the situation is revealed by the fact that the activity of bacitracin is enhanced by the presence of cationic and non-ionic surfactants [106] but decreased by anionic agents. The effect of non-ionic surfactants on the bactericidal activity of tyrothricin has been measured [107]. Some results are shown in Table 6.11. 

Uses Secondary surfactant for shampoos, bath gels, liquid soaps and facial cleansers cleansing agent viscosity builder solubilizer Features Mild works synergistically with anionic surfactants to build excellent foam stability and flash foaming characteristics compat. with other nonionic surfactants and most anionic and cationic surfactants Properties VCS 2 max. cl. thin liq. mild fatty odor water-disp. sp. gr. 0.999 HLB 7 acid no. 5.0 max. sapon. no. 145-155... 

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