Animal testing human screening

Test techniques for both tissue and blood responses of bio-materials have evolved significantly over the past several years. Increased government regulation of biomaterials in medical devices (as legislated in the U.S.A. in 1976 by the Medical Devices Amendments Act) has stimulated the development of a number of common vitro and vivo animal test systems for screening a wide variety of biomaterials and devices or implants for both tissue and blood responses. Tissue tests encompass a variety of in vitro and in vivo techniques. Blood tests include in vitro, ex vivo, and in vivo techniques. It is unlikely that successful medical devices or implants can be perfected for human use without such preliminary vitro and (especially) animal tests. 

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