5-Anilino-2-ethoxycarbonyl

Thiophene, 2-amino-3-cyano-5-phenyl-synthesis, 4, 888-889 Thiophene, 3-amino-4,5-dihydro-cycloaddition reactions, 4, 848 Thiophene, 2-amino-3-ethoxycarbonyl-ring opening, 4, 73 Thiophene, 2-amino-5-methyl-synthesis, 4, 73 Thiophene, 2-anilino-synthesis, 4, 923-924 Thiophene, aryl-synthesis, 4, 836, 914-916 Thiophene, 2-(arylamino)-3-nitro-synthesis, 4, 892 Thiophene, azido-nitrenes, 4, 818-820 reactions, 4, 818-820 thermal fragmentation, 4, 819-820 Thiophene, 3-azido-4-formyl-reactions... 

Aus den Synthesekomponenten C —N-C—N + C ist nur die Herstellung von 5-(2,6-Dimethyl-anilino)- -(2,6-dimethyl-phenyl)-4-(1-ethoxycarbonyl-ethenyl)-2-(4-nitro-phenyl)-imidazol in 89% Ausbeute aus 2,6-Dimethyl-phenylisocyanid mit 4-Nitro-benzoesaure-(2,6-dimethyl-phe-nylimid)-(2-ethoxycarbonyl-l-propenylidenamid) beschrieben306. 

Ethoxycarbonyl-2-(triphenylphosphoranylidenamino)vinyl]pyridine (43) with phenyl isocyanate gave a separable mixture of ethyl 8-anilino-l,7-naphthyr-idine-6-carboxylate (44) and an isomeric 2,6-naphthyridine derivative (formed by an alternative cyclocondensation) (reactants, PhMe, 20°C, 2 h then 180°C, sealed, 72 h 23% and 22%, respectively, after separation) analogs likewise.442... 

Ethoxycarbonyl-2-(triphenylphosphoranylideneamino)vinyl]pyridine (21) and phenyl isocyanate gave ethyl l-anilino-2,7-naphthyridine-3-carboxylate (22) (PhMe, 150°C 59%) analogs likewise).442... 

Benzyl-diethoxy- E2, 134 Benzyl-diisopropyloxy- E2, 134 Benzyl-ethyl-phenyl- -tosylimid E2, 113 Benzyl-methyl-phenyl- -tosylimid E2, 113 Benzyloxy-diphenyl- E2, 17, 18 Benzyloxy-ethoxy-hydroxy- E2, 187 Bis-[2-biphenylyl]- E2, 876 [2,6-bis-(2-tetrahydropyranyloxy-methyl)-phenyl]-Bis-[4-brom-anilino]-phenyl- E2, 416 Bis-[2-brom-ethoxy]-(2-brom-ethyl)- E2, 196 Bis-[butylthio]-ethyi- E2, 79, 408 Bis-[2-chlor-cthoxy]-butyl- E2, 196 Bis-[2-chlor-ethoxy]-(2-chlor-ethyl)- E2, 196 Bis-[2-chlor-ethoxy]-methyl- E2, 196 Bis- 2-chlor-ethoxy]-phenyl- E2, 196, 197, 202 Bis- 2-ehlor-ethoxy]-(2-phcnyl-vinyl)- E2, 196 Bis-(2-ehlor-ethoxy]-vinyl- E2, 196 Bis-j 2-chlor-ethyl]-methyl- E2, 205 Bis-[chlormethyl]-dodecyl- E2, 22 Bis-12-cyan-ethyl]- E2, 223 Bis- diethylamino]-butyl- E2, 486 Bis-[ l-cthinyl-butyl]-phenyl- E2, 197 Bis-[ethoxycarbonyl-methyl]-chlor- E2, 251 Bis-[ethylthio]-ethyl- E2, 408 Bis-[4-methoxy-aniliiio]-phenyl- E2, 416 Bis-[4-methyl-phenylJ-phenyl- K2, 105 Bis- 4-methyl-phcnyl]-phenyl- -phenylsulfonvlimid E2, 105... 

Thiazol 3-Amino-4-ethoxycarbonyl-5-(3-trifluormethyl-anilino)- E8a, 711 (NC-CH2-COOR + Ar-NCS)... 

Thiopheit 3-Amino-5-anilino-4-ethoxycarbonyl-2-nitro- E6a, 348 (NC-CH2 —COOR/NaOR 4-Ar —NCS/Br —CH2 — N02)... 

Isohamstoff l -(4-Chlor-anilino-carbonyl)-3-(ethoxycarbonyl-aminocarbonyl)-0-methyl- E4, 1354 (NH2 - NH-CO-NHR)... 

CeH5 N=N- -N ch3 CH, cooc2h5 (H3COl2S02 Chlor-benzol 80 1 3,4-Dimeihyl-5-ethoxycarbonyl-2-[4-( N-methyl-anilino)-phenylazo ]-... -chlorid 1 261... 

R = ch3 3(5)-Ani/ino-4-ethoxycarbonyl-513j-methyl-65% Schmp. 154° r=c6h3 3(5 )-Anilino-4-ethoxycarbonyl-5 (3)-phenyl-..68% Schmp. 230"... 

Ethoxycarbonyl-5-methyl-4-phenyl-2,3-dihydro-l,4-thiazin reagiert mit 80%igem Hydrazin-Hydrat (Ethanol lh RiickfluB) zu 4-(2-Anilino-ethylthio)-3(5)-hydroxy-5(3)-phenyl-lH-pyrazol (Schmp. 181-182< )1588a s-a-1589... 

Eine oxidative Dimerisierung von 3(5)-Amino-5(3)-anilino-4-ethoxycarbonyl-lH-pyrazol unter Knupfung einer N,N-Bindung ist mit Hilfe von Radikalen (Di-tert-butylperoxid/UV, Diben-zoylperoxid)561 oder durch anodische Oxidation moglich1613 ... 

Amino-3-anilino-l-( I-anilino-2-cyan-2-ethoxycarbonyl-ethenylazo ) -4-ethoxycarbonyl-lH-pyrazoI 80% Schmp. 143-145... 

Anilino-l-cyan-2-ethoxycarbonyl-methylthio-ethenyl)-.. 686 (R - Pyridinium Schwefelkohlenstoff, Kaliumcarbonat/Methyliodid) 2- (2,2-Bis-[methylthio]-l-pyridinium- ethyl)-...- iodid687... 

Anilino-2,3-diphenyl- -methylester 363 3- 2-[(2-Ethoxycarbonyl-ethenyl)-ethenyl-thio]-formyl (bzw. propanoyl)-amino - -ethylester 355... 

Amino-5-nitro- 87, 242, 243, 245, 272 2-(4-Amino-3-nitro-anilino)-5-ethoxycarbonyl-4-melhyl- 66... 

Benzoyl-2-(4-chlor-anilino)-4-phenyl- 132, 136 5-Benzoyl-2,4-dianilino- 140 2-Benzoyl-4,5-dimethyl- 261 5-Benzoyl-4-dimethylamino-2-methylamino- 140 2-(2-Benzoyl-hydrazino)-4-(ethoxycarbonyl-methyl)- 74... 

Brom-bcnzoyl)-2-(4-mcthyl-phcnyl)- 135 5-(4-Brom-benz.oyl)-2-methyllhio-4-phenyl- 132 5-( -Broni-bcnzyl)-4-hyd i oxy- 362 5-Brom-2-(4-brom-anilino)-4-phenyl- 240 2-Brom-4-(4-brom-phcnyl)- 154 2-Brom-5-tert.-butyl- 274 2-Brom-4-tcrt.-butyl-5-carboxy- 300 2-Brom-4-tert.-butyl-5-ethoxycarbonyl- 275 2-Brom-5-tert.-butyl-4-ethyl- 275... 

Ethoxy-anilino)-4-melhyl- 181, 223 2-(4-Ethoxy-anilino)-4-phenyl- 181 2-Ethoxycarbonyl- 25, 309... 

Amino-5(3)-anilino- 449 5-Amino-3-anilino-l-(l-anilino-2-cyan-2-ethoxy-carbonyl-ethenylazo)-4-ethoxycarbonyl- 709 5-Amino-4-anilinocarbonyl-3-methylthio- 472 3(5)-Amino-5(3)-anilino-4-ethoxycarbonyl- 599 5(3)-(2-Amino-anilino)-3(5)-phenyl- 566 5-Amino-l-arensulfonyl- 445 3(5)-Amino-4-aryl- 526 3(5)-Amino-5(3)-aryl- 469 5-Atnino-1-arylaminocarbonyl- 695 5-Amino-l-aryl-4-arylazo- 664 5-Amino-4-arylazo-l -benzolsulfonyl-3-methyl- 578 3(5)-Amino-5(3)-aryl-4-cyan- 467 5-Amino-l -aryl-4-cyan-... 

Anilino- 910 2-Benzylamino- 910 6-Ethoxycarbonyl-2-phcnyl- 922 2-Furyl- 907 2-(2-Furyl)- 911 2-Methyl- 911 2-Methylamino- 910 2-(4-Methyl-phenyl)- 911 2-Organoamino- 909 2-Phenyl- 911 2-(2-Phenyl-ethenyl)- 911 2-(2-Pyridyl)- 880 2-(2-Thienyl)- 911... 

A soln. of dimethyl N-(ethoxycarbonylmethyl)iminodithiocarbonate in THF added drop wise to a stirred soln. of K-/cr/-butoxide in the same solvent at -78° under N2, a soln. of phenyl isothiocyanate in the same solvent added slowly after 30 min, stirring continued at —78° for an additional 30 min, the mixture allowed to stand at room temp, for 2 h, then quenched with water 4-ethoxycarbonyl-2-methylthio-5-anilino-thiazole. Y 90%. F.e.s. C. Alvarez-Ibarra et al.. Heterocycles 27, 2177-83 (1988). 

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