Angioedema clinical presentation

Stanozolol Synthetic androgen Treatment of some clinical presentations of Behfet s syndrome and management of hereditary angioedema... 

The clinical presentations included a generalized rash or urticaria sometimes accompanied by nausea, malaise, vomiting, fever, arthralgias, and angioedema. 

Three years after introduction of aspirin into therapy, Hirschberg in Poznan, now in Poland, described the first case of a transient, acute angioedema/urticaria, occurring shortly after ingestion of aspirin. Reports of anaphylactic reactions to aspirin soon followed. The other major type of adverse reaction, acute bronchospasm, was described in the second decade of the 20th century. In 1920, Van der Veer reported the first death due to aspirin. The association of aspirin sensitivity, asthma and nasal polyps was first recorded by Widal in 1922. This clinical entity, later named the aspirin triad was popularized in 1968 by Samter and Beers [3], who presented a... 

Observational studies An open-label extension study of 20U/kg Cl-INH for hereditary angioedema evaluated 57 patients (19 male, mean age 31.9years) who experienced 1085 attacks and foxmd that the most common adverse effects were headache in 5 of tire 57 patients and nasopharyngitis in 3 of the 57 patients. One of 57 patients experienced an infusion-related reaction that occurred 2 min after the infusion and lasted 4.6 h. The patient was discontinued from the study. Further details were not provided in the report. Antibodies to Cl-INH were present in 19 of the 57 patients, although the authors reported no known clinically relevant association with the presence of anti-Cl-INH antibodies [32 ]. 

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