Angina pectoris case study

This ginseng exerts a major effect on the cardiovascular system. It dilates the coronary vessels and reduces vascular resistance, which results in increased coronary flow and decreased blood pressure. Chinese traditional medicine used this ginseng to arrest bleeding, remove blood stasis, and relieve pain. Recent studies have shown that, in the treatment of angina pectoris, this herb can produce a 95.5% improvement in symptoms. The herb usually can stop bleeding in cases of respiratory bleeding or vomiting of blood. 

The committee identified one study of an important and specific clinical outcome—incident ischemic heart disease—and four studies of cardiovascular mortality. Jain et al. (2007) examined the association between bone lead and incidence of ischemic heart disease (myocardial irrfarction or angina pectoris) in a prospective cohort of veterans in the Boston, Massachirsetts, area (Normative Aging Study 83 cases and 754 noncases) with 10 years of followup. The mean (SD) concentrations of baseline BLL, patella lead, arrd tibia lead were 7.0 (3.8) pg/dL, 36.8 (20.8) pg/g, and 24.2 (15.9) pg/g in cases arrd 6.2 (4.3) pg/dL, 30.6 (19.7) pg/g, and 21.4 (13.6) pg/g in noncases, respectively. SD increases in BLL and patella lead were significantly associated with a 27% (95% Cl of hazard ratio [HR] 1.01, 1.59) and a 29% (95% Cl of HR 1.02, 1.62) increased risk of ischemic heart disease. Compared with srrbjects who had BLLs under 5 pg/dL, those who had BLLs of 5 pg/dL or higher had an HR of 1.73 (95% Cl 1.05, 2.87). Weisskopf et al. (2009) conducted a strrvival analysis of mortality in the same cohort (an average of 8.9 years of followup) and found that men in the highest tertile of patella lead had HRs of 2.52 (95% Cl 1.17, 5.41) for all causes, 5.63 (95% Cl 1.73, 18.3) for cardiovascular disease, and 8.37 (95% Cl 1.29, 54.4) for ischemic heart disease. Baseline BLLs were not associated with cardiovascular mortality. 

Study of 110 cases of angina pectoris plasma concentrations of vitamin C, E and carotene were significantly inversely related to the risk of angina pectoris. However, the relation of vitamin C to risk was substantially reduced after adjustment for smoking. Only vitamin E remained inversely related to the risk of angina (Riemersma a/., 1991). 

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