Amperometric sensors, nitric oxide

Y. Lee, B.K. Oh, and M.E. Meyerhoff, Improved planar amperometric nitric oxide sensor based on platinized platinum anode. 1. Experimental results and theory when apphed for monitoring NO release from diazeniumdiolate-doped polymeric films. Anal. Chem. 76, 536-544 (2004). 

M. C. Frost, S. M. Rudich, H. Zhang, M. A. Maraschio, and M. E. Meyerhoff, In Vivo Biocompatibility and Analytical Performance of Intravascular Amperometric Oxygen Sensors Prepared with Improved Nitric Oxide-Releasing Silicone Rubber Coating, Anal. Chem. 2002, 74, 5942. 

By means of amperometric sensors a simultaneous determination of oxygen and hydrocarbons or nitric oxides is possible. For such sensors tube [vi,vii] or planar [viii] designs were described. The current measured is proportional to the oxygen concentration and the concentration of hydrocarbons and nitric oxides, respectively. 

D. Preparation and Measurement of Nitric Oxide with Amperometric Sensors.245... 

D. PREPARATION AND MEASUREMENT OF NITRIC OXIDE WITH AMPEROMETRIC SENSORS... 

Nitrite Nitrite is an important indicator of fecal pollution in natural waters as well as a potential precursor of carcinogenic species. A rush of flow and sequential injection spectrophotometric method based on Griess-type reactions has been proposed, also coupled to online sorbent enrichment schemes. The catalytic effect of nitrite on the oxidation of various organic species constitutes the basis of fairly sensitive spectrophotometric methods. Fluorometric methods based on the formation of aromatic azoic acid salts, quenching of Rhodamine 6G fluorescence, and direct reaction with substituted tetramine or naphthalene species have been also reported. Indirect CL methods usually involve conversion into nitric oxide and gas-phase detection as mentioned in the foregoing section. The redox reaction between nitrite and iodide in acidic media is the fundamental of a plethora of flow injection methodologies with spectrophotometric, CL, or biamperometric detection. New electrochemical sensors with chemically modified carbon paste electrodes containing ruthenium sites, or platinum electrodes with cellulose or naphthalene films, have recently attracted special attention for amperometric detection. 

Cha, W., Tung, Y.-C., Meyerhoff, M. E., Takayama, S. 2010. Patterned electrode-based amperometric gas sensor for direct nitric oxide detection within microfluidic devices. Anal. Chem. 82 3300-3305. 

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