Amoxicillin chemical structure

The penicillins (pen-uh-SILL-ins) are a class of antibiotic compounds derived from the molds Penicillium notatum and Penicillium chryAogenum. The class contains a number of compounds with the same basic bicyclic structure to which are attached different side chains. That basic structure consists of two amino acids, cysteine and valine, joined to each other to make a bicyclic ( two-ring ) compound. The different forms of penicillin are distinguished from each other by adding a single capital letter to their names. Thus penicillin F, penicillin G, penicillin K, penicillin N, penicillin 0, penicillin S, penicillin V, and penicillin X. A number of other antibiotics, including ampicillin, amoxicillin, and methicil-lin, have similar chemical structures. 

The 400 MHz spectrum of amoxicillin trihy ate in D20 adjusted to pD 8 with NaOD is shown in Figure 4. Chemical shifts re tive to external sodium dimethylsilapentane-l-sulphonate and assignments are listed below, using the numbers in the following structure-... 

A systematic chemical name for amoxicillin, from which a chemist should be able to write its complete structure, is 6-(p-hydroxy-a-aminophenylaceta-mido)penicillinic acid. 

S.M. Santos, J. Rocha, L. Mafra, NMR crystallography toward chemical shift-driven crystal structure determination of the P-Lactam antibiotic amoxicillin trihydrate, Cryst. Growth Des. 13 (6) (2013) 2390-2395. 

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