Antacids Amoxicillin

Clinically important, potentially hazardous interactions with amoxicillin, ampicillin, antacids, bacampicillin, calcium carbonate, carbenicillin, cloxacillin, digoxin, methotrexate, methoxyflurane, mezlocillin, nafcillin, oxacillin, penicillins, piperacillin, ticarcillin, zinc... 

Clinically important, potentially hazardous interactions with acitretin, aluminum hydroxide, amoxicillin, ampicillin, antacids, bacampicillin, betamethasone, bismuth, bromelain, calcium, carbenicillin, cholestyramine, doxacillin, corticosteroids, dairy products, dicloxacillin, didanosine, digoxin, food, glidazide, iron, isotretinoin, methicillin, methotrexate, methoxyflurane, mezlocillin, nafcillin, oxacillin, penicillins, piperacillin, retinoids, rocuronium, strontium ranelate, sucralfate, ticarcillin, vitamin A, zinc... 

Amoxicillin, clarithromycin, tetracycline, and metronidazoie have been used in various regimens for H. fy/on-associated GI ulcers, together with H2 blockers, proton pump inhibitors, and antacids e.g., "BMI" regimen bismuth, metronidazole, and tetracycline. 

Aluminium/magnesiium hydroxide and aluminium hydroxide do not significantly affect the bioavailability of amoxicillin or amoxicillin with clavulanic acid (co-amoxiclav). Antacids may reduce the absorption of the hydrochloride salt of pivampicillin. 

The pharmacokinetics of amoxicillin 1 g, and both amoxicillin and clavulanic acid (given as co-amoxiclav 625 mg), were not significantly altered by 10 doses of aluminium/magnesium hydroxide (Maalox) 10 mL, with the last dose given 30 minutes before amoxicillin. Another study found that four 40-mg doses of aluminium hydroxide (Aludrox) given at 20 minute intervals had no effect on the pharmacokinetics of either amoxicillin or clavulanic acid (given as co-amoxiclav 750 mg with the second dose of antacid). ... 

There would seem to be no reason for avoiding the concurrent use of antacids and amoxicillin or co-amoxiclav. 

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