5- Aminolevulinic acid dehydratase deficiency

ADDP (5-Aminolevulinic acid dehydratase-deficient porphyria... 

Genetic Glucose-6-phosphate dehydrogenase deficiency, glutathione deficiency, glutathione reductase deficiency, thalassemia, tyrosinemia, Wilson s disease, 6-aminolevulinic acid dehydratase deficiency... 

Alkyldihydroxyacetonephosphate synthase deficiency 2-Aminoadipate aminotransferase deficiency 2-Aminoadipic semialdehyde synthetase deficiency -Aminolevulinic acid dehydratase deficiency 2-Amino-/2-oxoadipic aciduria Amylo-l,6-glucosidase deficiency Amylopectinosis Andersen disease Androgen Insensitivity syndrome Apolipoprotein A-I deficiency Apolipoprotein B-lOO deficiency Apolipoprotein C-II deficiency... 

This work extends the study of iron deficiency by examining the effects of levulinic acid on thylakoid biosynthesis. This compound is a competitive inhibitor of -aminolevulinic acid dehydratase, an important step in porphyrin biosynthesis in cyanobacteria (J.A. Kipe-Nolt et al., 1978). This preliminary study is aimed at comparing membrane biosynthesis under iron deficient and levulinic acid inhibited conditions. The goal is to identify the factors which regulate lipid-protein and membrane assembly. 

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