3-Amino-2-hydroxypropyl-substituted

An oxidized stage of isohexide nitrates, wherein the remaining hydroxyl group is transformed into the ketone, gives rise to a number of derivatives 161, such as oximes, semicarbazones, acyclic and cyclic acetals, and hydra-zones.154 Among them, 3-amino-2-hydroxypropyl-substituted oxime ethers... 

Oxiranylmethyl)furo[3,2-/)]pyrrole-5-carboxylate (272) with morpholine undergoes oxirane ring opening to form the. -substituted derivative of methyl 4-(3-amino-2-hydroxypropyl)furo[3,2-/>]pyrrole-5-carboxylate (273). Using pyrrolidine as nucleophile the fused aza-lactone (274) is formed (Scheme 18) <95UP 701-01). 

Fig. 7.8. Illustrations of the one-dimensional polymeric chains of mono-substituted y -CyDs 2-0-[(S)-2-hydroxypropyl]-y -CyD (A), 6-deoxy-6-[(l-phenylethyl)amino]-y -CyD (B), 6-deoxy-6-[(l-cyclohexyl)amino]-y -CyD (C), and 6-deoxy-6-(phenylthio)- -CyD (D).

Trade Name Synonyms Mackanate IM t[Mclntyre http //www.mcintyregroup.com] Disodium isostearamido MIPA-sulfosuccinate Synonyms Butanedioic acid, sulfo-, 1-ester with N-(2-hydroxypropyl) isooctadecanamide, disodium salt Butanedioic acid, sulfo-, 1-[methyl-2-[(1-oxoisooctadecyl) amino] ethyl] ester, disodium salt Suifobutanedioic acid, 1-[methyl-2-[(1-oxoisooctadecyl) amino] ethyl] ester, disodium salt Definition Disodium salt of a substituted isopropanolamine half ester of sulfosuccinic acid Empirical C2sH47N08S 2Na Formula ... 

Af -Substituted 3-amino-2-hydroxypropyl methacrylates were prepared from glycidyl methacrylate and substituted amines as indicated in Scheme 1 [5] ... 

Table 2 Adhesive Tensile Strength Between CMP and PMMA with /V-Substituted 3-Amino-2-Hydroxypropyl Methacrylates... 

Dehydration of A7-substituted 3-amino alcohols with triphenylphosphine-CCU and Triethylamine produces aziridines in good yield (eq 15). This reaction has been successfully employed in the preparation of stable arene imines (eq 16). Azetidines can be obtained from the corresponding 3-aminoalk.anols (eq 17). Additionally, reaction of 2-(3-hydroxypropyl)piperidine under these conditions yields octahydroindolizine (eq 18). 

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