1 - Amino-2,2-dimethy 1-1 -

Dimethylaminoquinoline is converted into the 2-amino analog by potassium amide (liquid NHg, 20°, 18 hr). 4-Dimethy-laminoquinazoline exceeds the methylamino derivative in reactivity toward ammonium acetate or alkali amides. Hot acid or alkali... 

Cyclocondensation 2- [2-cyano-2-(2-pyridyl)ethenyl]amino -3-(dimethy-lamino)acrylates and 2-aminopyridines in boiling AcOH for 1-1.5 h afforded 3- [2-cyano-2-(2-pyridyl)ethenyl]amino -4//-pyrido[l,2-n]pyrimi-din-4-ones in low yields (01H(55)705, 01JHC869). 

A solution of 0.7 g of 2-(2-amino-N-methylacetamido)-5-chlorobenzophenone in 10 ml of a 50% solution (by weight) of diketene in acetone is refluxed for 3 hours and then evaporated to give a brown oil. The oil Is chromatographed on 200 g of silica gel using a 1 1 (by volume) mixture of ethyl acetate cyclohexane 25 ml fractions are collected. Fractions 11-14 are combined, mixed with chloroform, evaporated and triturated with ether to give 0.337 g of 11-chloro-8,12b-dihydro-2,8-dimethy 1-12b-phenyl-4H-[ 1,3]oxazino[3,2-dl [1,4] benzodiazepine-4,7 (6H)-dione as a pale yellow solid, MP 174°C to 176°C. 

A CSP with a smaller (i-cyclodextrin moiety (seven glucose units) immobilized on silica gel (ChiraDex ) is able to separate the dansyl-derivatives [5-(dimethy-lamino)-naphthalin-l-sulfonylchloride] of amino acids [26]. 

CN 1 - [(1,1 -dimethy lethy l)amino]-3- [2- [(tetrahydro-2-furanyl)methoxy ]phenoxy ]-2-propanol... 

CN 4-amino-3,5-dichloro-a-[[(l,l-dimethy]ethyl)amino)methyI]ben2enemethanol Iiydrochloride... 

Dimethy amino)-benzaldefyde-Acetic Acid-Phosphoric Acid Reagent... 

Allylmetallic reagents The ally] anions obtained by reductive metallation of ally I phenyl sulfides with lithium l-(dimethy amino)naphthalenide (LDMAN, 10, 244) react with a, 3-enals to give mixtures of 1,2-adducts. The regioselectivity can be controlled by the metal counterion. Thus the allyllithium or the allyltitanium compound obtained from either 1 or 2 reacts with crotonaldehyde at the secondary terminus of the allylic system to give mainly the adduct 3. In contrast the allylcerium compound reacts at the primary terminus to form 4 as the major adduct. 

Die Oxidation von 1-Amino-5,6-dimethy]-l,5-dihydro- mit Blei (IV)-acetat fiihrt unter Abspaltung von Stickstoff zu l, 2-DimethyI-5,6-dehydro-benzimidazol, das mit verschiedenen Dienen abgefangen werden kann655 z.B. ... 

J, NHj Ni l-( 1-Amino-ethyt)-3-( 2-amino-ethyl) -2,2-dimethy l-cyclo-hutan 80... 

S. Hanessian and E. Moralioglu, Chemistry of l-(dimethylamiiio)ethylklcne and a-(dimethyl-amino)benzylidene acetals. Utility as blocking groups for diols and for selective esterification. Tetrahedron Lett. 813 (1971) S. Hanessian and E. Moralioglu, Chemistry and synthetic utility of a-(dimethylamino)benzylidene and 1 -(dimethy lamino)ethylidene acetals. Con. J. Chem. 

Chemical names original 2-methylthio-4-methylamino-6- isopropylamino-5-triazine 2-methylthio-4-ethylamino-6-(1,2-dimethy lpropyl)-amino-a -triazine NA... 

Amino-1,4-dimethyl-1,8-naphthyridin-2(l/7)-one 7-Ami no-2,3-dimethyl-l,8-naphthyridin-4(l//)-one 2-Ami no-5,7-dimethy 1-4-oxo-1,4-dihydro-1,... 

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