3- Amino-4-benzylamino

Amino-3-benzylamino-l-methyl-4-nitro- 470 3(5)-Amino-5(3)-benzylamino-4-nitro- 470... 

Isophthaisaure 2,6-Dimethyl-4-dimethylamino- -bis-nitriloxid E5, 1591 (aus Bis-oxim) Malonsaure (Amino-benzylamino-methylen)- -methylester-nitril E15/2, 2156 (CC13 - NH-R) I,3i4-Oxadiazol 5-Morpholino-2-phenyl- E8c, 573 (Ar — CO — NH-NH-CO-NR2/POCl3) Phthalazine l,4-Dihydroxy-6-pyrrolidino- E9a, 752 (subst. Phthalanhydrid + N2H4) lH-Pyrazol 5-Carboxy-l-methyl-4-(4-methyl-anilino)- E8b, 633 (4-Br -> 4-NH-Ar)... 

Synonyms 3,5-Diamino-N-[amino(benzylamino)methylene]-6-chloro-pyrazinecarboxamide benzylamiloride Trade Names ... 

In addition to alcohols, some other nucleophiles such as amines and carbon nucleophiles can be used to trap the acylpalladium intermediates. The o-viny-lidene-/j-lactam 30 is prepared by the carbonylation of the 4-benzylamino-2-alkynyl methyl carbonate derivative 29[16]. The reaction proceeds using TMPP, a cyclic phosphite, as a ligand. When the amino group is protected as the p-toluenesulfonamide, the reaction proceeds in the presence of potassium carbonate, and the f>-alkynyl-/J-lactam 31 is obtained by the isomerization of the allenyl (vinylidene) group to the less strained alkyne. 

Amino groups a to nitrogen are hydrolyzed to the corresponding oxo compounds (as in the purines and pteridines) in bo h acid and alkaline conditions. Schiff bases are reduced to benzylamino derivatives with borohydride. 

Kinetic studies have been carried out on the displacement reactions of various chloroazanaphthalenes with ethoxide ions and piperi-dine. - 2-Chloroquinoxaline is even more reactive than 2-chloro-quinazoline, thus demonstrating the powerfully electrophilic nature of the -carbon atoms in the quinoxaline nucleus. The ease of displacement of a-chlorine in the quinoxaline series is of preparative value thus, 2-alkoxy-, 2-amino-, - 2-raethylamino-, 2-dimethyl-amino-,2-benzylamino-, 2-mercapto-quinoxalines are all readily prepared from 2-chloroquinoxaline. The anions derived from substituted acetonitriles have also been used to displace chloride ion from 2-chloroquinoxaline, ... 

Bis-[2-amino-1 -carboxy-athyl]- 634 Bis-[2-amino-2-carboxy-propyl]- 634 Bis-[4-benzylamino-phenyI]- 102 Bis-[4-brom-phenyI]-... 

Amino-l,1,1-trideutcro- 111 2-Amino-1 -(4-trimethylsilyl-phenyl)- 363 1 -Benzylamino- 351... 

Acetyl-phenyl- 635 4-Amino-3,5-dimethyl-phenyl- 102 2-Amino-4-hydroxy-phenyl- 692 4-Amino-phenyl- 685 4-Benzylamino-phenyl- 102 2,4-Dinitro-phenyl- 692 4-(2-Hydroxy-benzylamino)-phenyl- 102 2-(2-Methyl-butanoyl)-phenyl- 635 4-Methoxy-2,6-dimethyl-phenyl-102 (Nitro-phenyl)- 635 2-Nitro-phenyl- 680, 692 4-Nitro-phenyl- 685... 

C9H13NO 104-63-2) see Indeloxacine Phenmetrazine 7-(2-benzylaminoethyl)theophylline (C15H19N5O2 22680-61-1) see Fenetylline Theodrenaline benzyl [(2R,35)-3-amino-2-hydroxy-4-phenylbutyl](2-methylpropyl)carbamate monohydrochloride (C22H3[C1N20j 160232-11-1) see Amprenavir 2-benzylamino-l-(4-methoxyphenyl)propane (C17H21NO 43229-65-8) see Fenoterol Formoterol benzyl [3-[(2-aminophenyl)carbamoyl]propyl]methyl> carbamate... 

Briliant Blue FCF (E 133, FD C Blue No. 1, Cl Food Blue 2) is a triarylmethane dye disodium 3-[N-ethyl-N-[4-[[4-[N-ethyl-N-(3-sulfonatobenzyl)-amino] phenyl] (2-sulfonatophenyl)methylene]-2,5-cyclohexadiene-l-ylidene]ammoniome-thyl] benzenesulfonate (or disodium (4-(N-ethyl-3-sulfonato-benzylamino) phenyl)-a-(4-N-ethyl-3-sulfonatobenzylamino)cyclohexa-2,5-dienylidene)-toluene-2-sul-... 

Benzylamino-4-iV-benzyl-5-imino-4,5-dihydro-l,2,4-thiadiazole 5-[(l-Aminoethylidene)amino]-3-chloromethyl-l,2,4-thiadiazole... 

The reaction of 4-amino-3-aryl-5-(benzylamino) pyrazoles with ketoamines with the structure 4-RC6H4COCH2CH2NMe2 (R = H, Cl, Br, N02, MeO) in ethanol with acetic acid has been reported to afford a series of 1-benzyl-4,6-diary 1-2,3-dihydropyrazolo [3,4- >][l,4]diazepines <00HC231>. 

Methyl 2-(benzylamino)methyl-3-hydroxybutanoate Butanoic acid, 3-hydroxy-2-[[(phenylmethyl)amino]methyl]-, methyl ester (R, R )- (118559-03-8) ... 

B. Methyl 2-(benzylamino)methyl-3-hydroxybutanoate. A dried, 2-L, onenecked, round-bottomed flask, equipped with a magnetic stirring bar, is charged with 68.7 g (0.53 mol) of methyl 3-hydroxy-2-methylenebutanoate and 800 mL of anhydrous methanol. After the addition of 57.7 mL (0.53 mol) of benzylamine (Note 1), the mixture is stirred at room temperature for 48 hr (Note 3). The methanol is removed under reduced pressure to leave 125.6 g (100%) of the amino ester as a clear oil, essentially pure by 1H NMR analysis (Note 4). 

Sinou and coworkers evaluated a range of enantiopure amino alcohols derived from tartaric acid for the ATH reduction of prochiral ketones. Various (2R,iR)-i-amino- and (alkylamino)-l,4-bis(benzyloxy)butan-2-ol were obtained from readily available (-I-)-diethyl tartrate. These enantiopure amino alcohols have been used with Ru(p-cymene)Cl2 or Ir(l) precursors as ligands in the hydrogen transfer reduction of various aryl alkyl ketones ee-values of up to 80% have been obtained using the ruthenium complex [93]. Using (2R,3R)-3-amino-l,4-bis(benzyloxy)butan-2-ol and (2R,3R)-3-(benzylamino)-l,4-bis(benzyloxy)butan-2-ol with [lr(cod)Cl]2 as precursor, the ATH of acetophenone resulted in a maximum yield of 72%, 30% ee, 3h, 25 °C in PrOH/KOH with the former, and 88% yield, 28% ee, 120 h with the latter. 

Ethyl 6-amino-4,5-difluoro-l-methyl-7-oxo-li/,7//-pyrido[3,2,l-i/]cinno-line-8-carboxylate (84, R = H) was prepared from the 6-benzylamino derivative 84 (R = CH2Ph) by catalytic debenzylation over Pd/C in a mixture of ethanol and acetic acid (92EUP470578,92MIP1). 

Cl NH 1 ch2 S02—CgHs H4NC1 Ampulle H5C2 —OH pH -8 155. 18 h 2-Amino-5-(4-benzokulfonyl-benzylamino )-3H-(jiaphtho [/,2-d imida-zoiy 18 351... 

Der Austausch der Carbonyl-Gruppe bei Sydnonen durch die Imino-Funktion ist im allge-meinen nicht moglich. Eine Ausnahme bilden offenbar 3-Acylamino-sydnone. So erhalt man aus 4-Benzoyl-3-(benzyl-bromacetyl-amino)-sydnon bei — 78 in fliissigem Ammoniak 4-Benzoyl-3-benzylamino-sydnon-imin14. ... 

So erhalt manz. B, aus 2-Benzylamino-benzoesaure-acyloximid-amiden beim Kochen in Wasser 2-Amino-benzimidazole, wahrend in ethanolischerNatronlauge oder in Pyridin 3-(2-Benzyl-amino-phenyl)-l,2,4-oxadiazole entstehen213. 

Ein neueres Verfahren fur den Ersatz eines Chlor-Atoms durch eine Amino-Gruppe in substituierten Allyl-chloriden verlauft ilber Allylpalladium-Komplexe als Zwischenstufen. So erhalt man z. B. durch Umsetzung von 2-Acetoxy-5-chlor-3-hexen mit drei Aquiva-lenten Dimethylamin bzw. Benzylamin in Tetrahydrofuran in Gegenwart von 2-3% Pal-ladium(TT)-acetat/4-6% Triphenylphosphan bei 20° innerhalb 3 bzw. 9 Stunden 2-Acet-oxy-5-dimethylamino-3-hexen (80%) bzw. 2-Acetoxy 5-benzylamino-3-hexen (56%) im letzteren Fall wird das ebenfalls mogliche tertiare Amin (Dibenzylierungsprodukt) nicht isoliert1. 

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