Amine oxides amines, prim

Bis-[dimethylamino]- -2,4-bis-oxid aus prim. Amin und Phosphorsaure-tris-[dimethylamid] E2, 660... 

An der Oberflache einer Silberelektrode erzeugtes Silber(II)-oxid oxidiert prim. Amine zum Nitril neben Alde-hyd92 z.B. ... 

Tetrachloroauric(III) acid Oxidation of prim, amines to 0X0 compds. 

Setzt man Di-1 -alkinyl-phosphanoxide und prim. Amine (z. B. Butylamin) im Molverhalt-nis 1 2 um, so entstehen Bis-[2-oxo-alkyl]-phosph an oxide bei der protonen-kata-lysierten Hydrolyse der intermediaren Bis-enamine418. 

Zur Oxidation prim. Amine zu Aldehyden ist Dihydrogenperoxid wenig geeignet [s.Bd. X/4, S. 123ff. (1968)], dagegen liefert die Oxidation mit Peroxodisulfat Aldehyde in sehr guten Ausbeuten (bis 96%), s.Bd. IV/lb, S.177f. mit Arbeitsvorsehrift. 

Prim. Amine lassen sich auch mit Silberpyridin-2-carboxylat zu Aldehyden oxidieren88, al-lerdings sind die Ausbeuten wesentlich schlechter als bei der Peroxidisulfat-Oxidation, da die prim, gebildeten Iminc zu Nitrilen als Hauptprodukt dehydriert werden89, vgl,9°. In Dimethylsulfoxid als Losungsmittel werden bessere Ausbeuten erzielt91 ... 

Prim ary and secondary amines are oxidized to the respective hydroxji amines, and further oxidation to the nitro compound occurs in the case of priniary amines. 

Since the azomethines may be hydrolyzed to oxo compounds, this reaction provides an efficient oxidative deamination of prim, amines and an effective degradation procedure for sec. amines. F. e. s. S. G. Gohen and R. J. Baum-garten, Am. Soc. 87, 2996 (1965). 

Platinum oxide j hydrogen chloride Prim, amines from nitriles with simultaneous N-debenzylation 1,2-Diamines... 

Palladium oxide-barium sulfate Prim, from sec. amines s. 13, 266... 

Silver carbonate-on-Gelite has been recommended for the oxidation of alcohols to aldehydes and ketones. It does not attack hindered hydroxyl groups Prim, amines can be converted to ketones under mild conditions through prototropic isomerization of certain Schiff bases A variety of aldehydes, including deu-terio-, a, -ethylene-, and cycloalkane-aldehydes have been obtained in a novel manner from dihydro-1,3-oxazines Non-con-... 

Mesityl oxide refluxed 16 hrs. in water with a precipitated Ni-catalyst prepared from NiGl2 and Zn-dust in water isobutyl methyl ketone. Y 95%. - These convenient reductions do not require hydrogen. F. e., e.g. prim, amines from nitriles, s. K. Sakai and K. Watanabe, Bull. Chem. Soc. Japan W, 1548 (1967). 

Prim., sec., and tert. amines containing hydrogen on carbon a to nitrogen are oxidatively hydrotyzed to the corresponding 0x0 compounds by buffered permanganate. This new method is simple, rapid, and efficient. - E Dicyclo-hexylamine added rapidly at 50-75 to a stirred soln. of K-permanganate and Ca-sulfate in aq. terf-butanol, and distilled rapidly cyclohexanone. Y 67% 85% if isolated as the 2,4-dinitrophenylhydrazone. - Zn-sulfate may be used instead of Ca-sulfate as buffer. F. e. s. S. S. Rawalay and H. Shechter, J. Org. Chem. 32, 3129 (1967). 

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