3- amido-3,6-dideoxy

Benzyl 2-acetamido-6-0-benzyl-2,4-dideoxy-4-fluoro-a-D-glucopyrano-side and the corresponding free sugar were prepared from benzyl 2-acet-amido-3-0-allyl-6-0-benzyl- (or -3,6-di-0-benzyl)-2-deoxy-a-D-galacto-pyranoside by treatment with DAST (in diglyme). 

V"-Fluoren-9-ylmethoxycarbonyl-3-0- 2-acetamido-2-deoxy-3,4-0-isopropyKdene-6-0-[methyl(5-acet-amido-4,7,8,9-tetra-0-acetyl-3,5,-dideoxy-D-glycero-a-galacto-2-nonulopyranosyl)onate]-a-D-galacto-pyranosylJ-L-threonme Benzyl Ester (84) 11251... 

A series of interesting derivatives was prepared21,69 starting from phosphoranes having maleimido, amido, and nitryl functions. These products were 2,4 3,5-di-0-benzylidene-l-deoxy-l-(2,5-dioxo-3-pyr-rolylidene)-D-ribitol (99a), its N-phenyl derivative (99b), 2,4-0-benzylidene-1 -deoxy- l-(2,5-dioxo-3-pyrrolylidene)-D-ribitol (99c), 4,6 5,7-di-0-benzylidene-2,3-dideoxy-D-nbo-hept-2-enonamide (100), 2,3-dideoxy-D-giuco-oct-2-enonamide 4,5,6,7,8-pentaacetate (101), 4,6 5,7-di-0 - benzylidene - 2,3 - dideoxy - D - ribo-hept-2-enononitrile (102), and 2,3-dideoxy-D-g(uco-oct-2-enononitrile 4,5,6,7,8-pentaacetate (103). Derivatives 99a-99c were prepared for use in the... 

Interestingly, Matsumoto and Osawa196 reported that p-nitrophenyl (and phenyl) 2-acetamido-2-deoxy-/3-D-glucopyranoside, at a concentration of 10 mg/ml, did not inhibit the agglutination reaction between the potato lectin and human erythrocytes, whereas both p-nitrophenyl 2-acetamido-2,6-dideoxy-/3-D-gIucopyranoside and phenyl 2-acet-amido-3-0-(D-l-carboxyethyl)-2-deoxy-j3-D-glucopyranoside, at a level of 5 mg/ml, completely inhibited the hemagglutinin reaction. The... 

Prediction of the composition of the equilibrium mixture on the basis of presumed conformational stability or instability is uncertain, as is shown by the example of 2,5-bis(acetamido)-2,5-dideoxy-D-xylose, obtainable by periodate cleavage of 3,6-bis(acetamido)-3,6-dideoxy-D-gulopyranose. From the reaction mixture, 2,5-bis(acet-amido)-2,5-dideoxy-D-xylofuranose can be obtained crystalline in 36% yield no report was made as to any content of pyranose. Other 5-acetamido-5-deoxyxylose derivatives, for example, methyl 3,5-bis(acetamido)-2-S-benzyl-3,5-dideoxy-2-thio-/3-D-xylofuranoside," were not susceptible to hydrolysis. ... 

R. D. Marshall and A. Neuberger, Carbohydrates in protein. VIII. The isolation of 2-acet-amido l-(L-P-aspartamido)-l,2-dideoxy-p-D-glucose from hen s egg albumin. Biochemistry, 3 (1964) 1596-1600. 

D-Acosamine (2,3,6-dideoxy-3-amino-D-otraZ>mo-hexose) has been isolated from hydrolysis of the antibiotic sporoviridin/ which contains at least two acosamine moieties in addition to viosamine (4-amino-4,6-dideoxy-D-glucose). 2-Acet-amido-glucal has been isolated from the urine of patients with sialuria and 1,5-dideoxy-l,5-imino-D-mannitol is present in the legumes Lonchocarpus sericens. ... 

A short synthesis of 3,4,6-tri-0-benzyl-l,5-dideoxy-l,5-imino-D-mannitol has been achieved by acid-catalysed hydrolysis, followed by controlled reductive amination of a per-benzylated l,6 -diazido-l,6 -dideoxy-sucrose derivative. Further transformation by way of an azide displacement of a 2-0-triflyl derivative afforded ultimately 2-acetamido-l,2,5-trideoxy-l,5-imino-D-glucitol (2-acet-amido-1,2-dideoxynojirimycin). ... 

Me glycoside, Fi,2-Di-Ac Methyl 3-acet-amido-2-0-acetyl-3,6-dideoxy-a-L-gluco-pyranoside [10350-08-0]... 

Me glycoside, H,4,6-tri-Ac Methyl 2-acet-amido-4,6-di-0-acetyl-2,3-dideoxy-a-D-liho-hexopyranoside [61348-65-0]... 

Me glycoside, fi,2,4-tri-Ac Methyl 3-acet-amido-2,4-di-0-acetyl-3,6-dideoxy-x-D-mannopyranoside C13H21NO7 303.311 Cryst. (Me2CO). Mp 140-141°. [a]g +33 (c, 1.0 in EtOH). 

CgH,5N04 189.211 Cryst. (CftHe/cyclohexane). Mp 132°. Me glycoside, Yi,0-di-Ac Methyl 2-acet-amido-3-0-acetyl-2,4-dideoxy-a-Di,-ety-thto-pentopyranoside [82753-74-0]... 

Aminoethylamide of 2-hydroxy- ethyl a-ketoside of S-acet-amido-3,5-dideoxy-D- /ycero-D-ga/ucm-2-nonulosonic acid ... 

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