Amido acids benzene

There is obtained from 4-[)3-[5-methyl-isoxazolyl-(3)-carboxamido]-ethyl]-benzene-sulfonamide (prepared from 5-methyl-isoxazole-(3)-carboxylic acid chloride and 4-()3-aminoethyl)-benzene-sulfonamide hydrochloride, MP 213° to 214°C in pyridine) and chloroformic acid methyl ester, in a yield of 69%, the compound N-[ [-4-[)3-[5-methyl-isoxazolyl-(3)-carbox-amido] -ethyl] ] -benzene-sulfonyl] ] -methyl-urethane in the form of colorless crystals of MP 173°C. 

In the first case, reaction with amines leads to amides amido acids formed when amines react with cyclic anhydrides can be recyclized to cyclic imides (p. 344). When mixed acyclic or asymmetrical cyclic anhydrides react, a mixture of products can be formed, although the stronger acid usually gives an ester (or amide) (56). Reaction of alcohols with anhydrides very often takes place even in the cold certain anhydrides, however, are resistent to heat and can be crystallized from ethanol (57) they can be cleaved by heating with sodium ethoxide in ethanol or benzene. If the acids formed by hydrolysis are solid and suitable for identification, this procedure can be considered as the simplest for identification purposes. When anhydrides of liquid acids are to be identified, the reaction with aromatic amines is generally employed mixed anhydrides are best identified by chromatography of acids formed on alkaline hydrolysis. 

Salmon-red is prepared in an analogous manner from amido-benzene-azonaphthionic acid, and has the formula ... 

There is thus obtained from the higher members (compounds having five or more carbon atoms) of the amides, first the primary amine, and secondly, the nitrile of the next lower acid. In the aromatic series, the reaction for the preparation of primary amines, which contain the amido group in the benzene ring, is not of general importance, since these... 

If one molecule of a diazo-compound is allowed to act on one molecule of a primary amine, the acid radical of the former unites with the hydrogen atom of the latter, upon which the organic residues combine, as in the formation of the azo dyes. In this case, an amido-hydrogen atom is eliminated, so that a compound containing a chain of three nitrogen atoms is formed in the formation of an azo dye, one of the benzene-hydrogen atoms of the amine is eliminated ... 

In general, azo-, hydrazo-, and amido-compounds result from the electrolytic reduction of nitro-com-pounds. In this way Kendall obtained aniline from nitro-benzene, and Elbs and Haussermann prepared the normal reduction products of nitfo-phenol. The formation of azoxy-, azo-, amido-, or hydrazo-com-pounds was dependent upon whether acid or alkaline solutions were employed. If nitro-benzene is reduced in a concentrated acetic or formic acid solution, to which a few drops of concentrated sulphuric acid (to increase the conductivity) have been added, the corresponding salts of benzidene result a fact further confirmed by Lob. ... 

Various precursors for amido diamine [79] (figure 12) such as N,N -bis(4-aminophenyl)-2,5-bis [(isopropyloxy)carbonyl]benzene-1,4-dicarboxamide (PDPM), N,N -bis(3-aminophenyl)-2,5-bis[(isopropyloxy)carbonyl]benzene-1,4-dicarboxamide (MDPM), N,N -bis(4-aminophenyl)-4,4 (4,3 or 3,3 )-bis[(isopropyloxy) carbonyl]-biphenyl-3,3 (3,4 or 4,4 )-dicarboxamide (PDBP), N,N -bis(3-aminophenyl)-4,4 (4,3 or 3,3 )-bis[(isopropyloxy)carbonyl]-biphenyl-3,3 (3,4 or 4,4 )-dicarboxamide (MDBP) was reacted with 6FDA to prepare alternating copolyimide via alternating copoly(amic acid ester)... 

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