Alzheimer s disease cholinesterase inhibitors

Until recently there was no effective pharmacological treatment for Alzheimer s disease. Cholinesterase inhibitors are now available, but their effects are relatively small and only a proportion of patients respond (Burns et al, 1999). How should pharmacological budgets be spent on patients at the end of their life, and who should benefit when the improvements are small Most studies showed that donepezil gave a net... 

Doody RS. Current treatments for Alzheimer s disease cholinesterase inhibitors. J Clin Psychiatry 2003 64(Supplement 9) 11-17. 

Alzheimer s disease Cholinesterase inhibitors, antipsychotics Mini Mental Status Examination, gastrointestinal complaints, number of hallucinations, liver function tests (tacrine)... 

Besides their use in Alzheimer s disease, cholinesterase inhibitors have been extended to treat other dementias and related illnesses, which may include vascular dementia, dementia with Lewy Bodies, dementia associated with Parkinson s, mild cognitive impairment, and mixed dementia. Research is particularly important in this area since it is not uncommon for Alzheimer s disease to be co-morbid with other types of dementia. Therefore, it is important to devote a section briefly discussing recent flndings and the use of... 

---