Allergy diagnosis

The application and development of new in vitro diagnostic techniques aims to enable physicians to reach an allergy diagnosis with no risk for the patient. This is particularly desirable in the case of serious reactions such as anaphylaxis, by confirming the existence of an anaphylactic reaction and differentiating between individuals which present with sensitization but no cUnical symptoms following exposure to the allergen from those that show a serious clinical reaction. 

Hagendorens MM, Schuerwegh AJ, De Clerk LS, si Stevens WJ Flow-assisted allergy diagnosis current appheaUons and future perspectives. Allergy 2006 61 1028-1039. 

Perform allergy diagnosis (after 3-4 weeks including in vitro diagnosis, skin test and if necessary provocation tests)... 

Taylor, J.S. and Erkek, E., Latex allergy diagnosis and management, Dermatol. Then, 17, 289, 2004. 

Choquet-Kastylevsky, G. Vial, T. and Descotes, J. (2001). Drug allergy diagnosis in humans possibilities and pitfalls. Toxicology 158 1-10. 

In the recent past great efforts to improve food allergy diagnosis have been undertaken. By the use of DNA technology more than 50 food allergens have been produced in the recombinant form. 

Department of Molecular Biology Christian Doppler Laboratory for Allergy Diagnosis and Therapy University of Salzburg Salzburg, Austria... 

Asero, R., Ballmer-Weber, B. K., Beyer, K., Conti, A., Dubakiene, R., Fernandez-Rivas, M., et al. (2007). IgE-Mediated food allergy diagnosis Current status and new perspectives. Mol. Nutr. Food Res. 51,135-147. 

Helbling A, Gayer F, Pichler WJ, Brander KA Mushroom (Basidiomycete) Allergy Diagnosis established by skin test and nasal challenge. J Allergy Clin Immunol 1998 102 853-858. 

Moneret-Vautrin DA (2002). [Food allergy diagnosis]. Allerg. Immunol (Paris), 34 241-244. 

Another test for allergy diagnosis is the lymphocyte transformation test (LTT) which, if positive, would almost certainly prove such a diagnosis. The result of LTT in one of the patients in whom allergy to suxamethonium seemed very likely is shown in Fig. 2. Thymidine uptake was increased in the presence of suxamethoni-... 

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